Fig. 7
From: Multiparametric MRI evaluation of bone sarcomas in children
Ewing sarcoma of the distal femur in a 9-year-old boy. a-d) Pre-treatment. a Axial contrast-enhanced fat-suppressed T1-weighted MR image before treatment shows a large tumor heterogeneously enhancing (short arrows) with internal necrosis (*). b Automated volumetry of the mass is around 285 cc. c and d Axial DWI and ADC map images show restricted diffusion in the periphery of the lesion (arrows). Post-treatment. e Axial contrast-enhanced fat-suppressed T1-weighted MR image after treatment shows increase of the internal necrosis of the mass (*) with persisting peripheral enhancement (short arrows). Note soft tissue inflammation not present in the previous MRI (long arrow). f Automated volumetry of the mass is around 350 cc. g and h Axial DWI and ADC map images show mild linear restricted diffusion of the periphery (arrows). i Histogram of ADC maps performed before and after treatment shows an increase of the ADC mean values from 0.79 mm2/s to 1.41 mm2/s