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Table 2 Cox regression analysis for a progression of eGFR categories within 5 years among propensity score-matched participants

From: Impact of CT-determined low kidney volume on renal function decline: a propensity score-matched analysis

 

Univariate

Multivariate

HR

95% CI

p

HR†

95% CI

p

Low kidney volume group

1.52

1.03–2.23

0.04

1.64

1.09–2.45

0.02

Sex (male)

1.12

0.74–1.69

0.59

1.00

0.61–1.63

0.99

Age (ref: 40–49 years old)

 50–59

1.56

0.92–2.64

0.10

1.35

0.77–2.37

0.30

 60–69

1.72

0.98–3.03

0.06

1.42

0.75–2.70

0.28

70

3.12

1.70–5.71

 < 0.01

1.91

0.93–3.92

0.08

BMI (ref: 18.5–25)

  > 25

1.14

0.72–1.80

0.58

1.13

0.68–1.86

0.64

  < 18.5

0.83

0.33–2.04

0.68

0.80

0.31–2.09

0.65

Current smoker

0.67

0.37–1.22

0.19

0.72

0.38–1.36

0.31

Hypertension

1.36

0.93–1.99

0.12

1.27

0.83–1.94

0.27

Diabetes

0.71

0.26–1.94

0.51

0.45

0.15–1.32

0.14

Low EF

1.45

0.20–10.38

0.71

1.71

0.22–13.49

0.61

eGFR (ref: 80 mL/min/1.73 m2)

 70–79

5.47

0.70–42.71

0.11

4.94

0.63–38.64

0.13

 60–69

65.13

9.08–467.24

 < 0.01

56.27

7.81–405.35

 < 0.01

Low serum albumin

1.39

0.93–2.07

0.11

1.08

0.70–1.67

0.73

High serum uric acid

1.70

1.16–2.50

0.01

1.37

0.87–2.15

0.18

Hematuria ( 2 +)

1.18

0.48–2.91

0.71

1.78

0.66–4.81

0.26

Proteinuria ( 2 +)

1.02

0.14–7.32

0.98

0.60

0.07–4.85

0.63

  1. HR Hazard ratio, BMI Body mass index, CI Confidence interval, EF Ejection fraction, eGFR estimated glomerular filtration rate
  2. p < 0.05 is indicated in italics for significance