Association of lower extremity peripheral arterial disease with quantitative muscle features from computed tomography angiography

Insights into Imaging

Table 4 Comparison of CTA score and logistic regression models for PAD prediction

Evaluation index	CTA runoff score	LRM-I	LRM-II
Omnibus test^†	…	< 0.001	< 0.001
Hosmer and Lemeshow test^‡	…	0.19	0.90
AUC (95% CI)	0.81 (0.69, 0.92)	0.84 (0.73, 0.94)	0.89 (0.80, 0.97)
p value of AUC	< 0.001	< 0.001	< 0.001
Sensitivity	75 (15/20)	80 (16/20)	80 (16/20)
Specificity	75 (27/36)	81 (29/36)	83 (30/36)
Classification accuracy	75 (42/56)	80 (45/56)	82 (46/56)
Cutoff value^a	9.50	0.35	0.43

Abbreviations: CTA Computed tomography angiography, PAD Peripheral arterial disease, LRM Logistic regression model, AUC Area under curve, CI Confidence interval
^†p value of Omnibus test
^‡p value of Hosmer and Lemeshow test
^aSelection criterion of the cutoff value: the highest value of Youden index (sensitivity + specificity − 1)