The paradox of MRI for breast cancer screening: high-risk and dense breasts—available evidence and current practice

Insights into Imaging

Table 3 Breast MRI screening: available evidence, recommendations, and adoption in women at high risk and in women with dense breasts

Available evidence, recommendations/guidelines, and adoption	Breast MRI screening
	High risk	Dense breasts
RCT: mortality reduction	No	No
RCT: interval cancer reduction	No	Yes (in 2019)^a,c
RCT: favourable shift in tumour stage upon detection	Yes, in 2019^d	Yes (in 2019)^a,c,e
Test accuracy comparative studies	Yes, since 2000^f	Yes (in 2020)^b,g
Recommendations/guidelines	Since 2006−2007^h,i	2018−2023^{j, k}
Adoption by healthcare systems	Yes	No