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Table 1 Characteristics of patients with and without major endpoint

From: Prognostic value of right atrial strains in arrhythmogenic right ventricular cardiomyopathy

 

No endpoints

Endpoints

p value

Demographics

 Age (years)

44 ± 16

42 ± 20

0.504

 Men

47 (68)

21 (58)

0.319

 Hypertension

16 (23)

7 (19)

0.660

 Diabetes

4 (6)

2 (6)

0.664

Task force criteria

 Echocardiographic TF major criterion

26 (38)

13 (36)

0.874

 Echocardiographic TF minor criterion

22 (32)

12 (33)

0.880

 RV angiography

58 (84)

29 (81)

0.651

 ECG major repolarization criterion

17 (25)

13 (36)

0.217

 ECG minor repolarization criterion

16 (23)

9 (25)

0.836

 ECG major depolarization criterion

4 (6)

2 (6)

0.664

 ECG minor depolarization criterion

32 (46)

18 (50)

0.724

 Arrhythmias major criterion

19 (28)

7 (19)

0.362

 Arrhythmias minor criterion

31 (45)

19 (53)

0.445

 Family history

15 (22)

9 (25)

0.706

 CMR major criterion

50 (72)

27 (75)

0.780

 CMR minor criterion

12 (17)

2 (6)

0.770

Clinical presentation

 Recent cardiac syncope

5 (7)

8 (22)

0.027

 NVST

28 (41)

23 (64)

0.023

 24-h PVC count

983 (385–2529)

2580 (475–4422)

0.010

 Leads with anterior and inferior TWI

2 (1–3)

3 (2–4)

0.001

 5-yr ARVC risk score

0.22 (0.11–0.38)

0.35 (0.17–0.72)

0.012

CMR parameters

 RVEDVI (mL/m2)

116.32 (87.21–146.30)

121.69 (90.49–167.16)

0.181

 RVESVI (mL/m2)

73.78 (51.90–109.57)

87.94 (69.49–135.55)

0.037

 RVEF (%)

32.89 ± 12.66

24.86 ± 11.37

0.002

 RV GLS (%)

 - 8.49 (- 11.45 to - 5.94)

 - 5.55 (- 8.45 to - 3.74)

0.003

 RV GCS (%)

 - 6.72 (- 10.96–3.20)

 - 4.97 (- 8.71 to - 1.73)

0.078

 RV GRS (%)

19.10 (10.66–30.07)

12.14 (4.38–20.37)

0.008

 RV LGE presence

47 (68)

22 (61)

0.472

 RV WMA

57 (83)

28 (78)

0.550

 RV fatty infiltration

18 (26)

11 (31)

0.627

 RAEDVI (mL/m2)

43.58 (33.59–59.12)

43.44 (30.47–95.90)

0.466

 RAESVI (mL/m2)

21.07 (15.76–30.93)

24.64 (16.95–50.91)

0.142

 RAEF (%)

49.63 (44.78–55.95)

45.51 (40.89–49.51)

0.009

 RA reservoir strain (%)

27.10 (24.00–36.75)

24.20 (11.88–27.50)

0.001

 RA conduit strain (%)

14.20 (9.15–19.35)

11.55 (6.18–13.58)

0.004

 RA booster strain (%)

14.00 (11.35–16.70)

10.45 (5.05–14.18)

 < 0.001

 RA reservoir strain rate (sec-1)

1.60 (1.10–1.95)

1.10 (0.73~1.50)

 < 0.001

 RA conduit strain rate (sec-1)

 - 0.90 (- 1.35 to - 0.70)

 - 0.65 (- 0.80 to - 0.43)

 < 0.001

 RA booster strain rate (sec-1)

 - 1.60 (- 1.90 to - 1.20)

 - 1.30 (- 1.60 to - 0.80)

0.007

LV involvement analysis

 LVEF (%)

58.80 (50.35–61.94)

32.07 (22.44–39.31)

 < 0.001

 LV LGE presence

33 (48)

29 (81)

0.001

 LV WMA

20 (29)

26 (72)

 < 0.001

 LV fatty infiltration

27 (39)

23 (64)

0.016

 LV Involvement

34 (49)

29 (81)

0.002

  1. Values are mean ± SD, n (%), or median(25th–75th)
  2. RV right ventricular, ECG electrocardiogram, NVST nonsustained ventricular tachycardia, PVC premature ventricular contraction, TWI T-wave inversion, RVEDVI right ventricular end-diastolic volume index, RVESVI right ventricular end-systolic volume index, RVEF right ventricular ejection fraction, GLS global longitudinal strain, GCS global circumferential strain, GRS global radial strain, RAEDVI right atrial end-diastolic volume index, RAESVI right atrial end-systolic volume index, LGE late gadolinium enhancement, WMA wall motion abnormalities, RAEF right atrial ejection fraction, LV left ventricular, LVEF left ventricular ejection fraction. Five-year ARVC risk score, 1 − 0.8396exp (LP) where LP = 0.49*sex − 0.022*age − 0.66*history of recent cardiac syncope + 0.81*history of NSVT + 0.17*ln(24 h PVC count) + 0.11*Sum of anterior and inferior leads with TWI − 0.025*RVEF [20]