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Table 1 Variables of clinic, radiology and DECT in the training and validation cohorts

From: Development and validation of a model for predicting the expression of Ki-67 in pancreatic ductal adenocarcinoma with radiological features and dual-energy computed tomography quantitative parameters

Variables

Training cohort (n = 100)

Validation cohort (n = 43)

Clinical characteristics

 Gender (%)

  Male

56 (56.0)

25 (58.1)

  Female

44 (44.0)

18 (41.9)

 Age (mean ± SD)

62.60 ± 10.55

62.49 ± 9.74

 BMI (mean ± SD)

22.31 ± 2.76

21.57 ± 3.33

 CEA (%)

  Normal

69 (69.0)

36 (83.7)

  Elevated

31 (31.0)

7 (16.3)

 CA-125 (%)

  Normal

61 (61.0)

30 (69.8)

  Elevated

39 (39.0)

13 (30.2)

 CA-199 (%)

  Normal

20 (20.0)

7 (16.3)

  Elevated

80 (80.0)

36 (83.7)

Radiological features

 Tumour location (%)

  Head and neck

70 (70.0)

27 (62.8)

  Body and tail

30 (30.0)

16 (37.2)

 CT-reported T stage (%)

  T1–T2

54 (54.0)

23 (53.5)

  T3–T4

46 (46.0)

20 (46.5)

 CT-reported regional LN status (%)

  Negative

49 (49.0)

19 (44.2)

  Positive

51 (51.0)

24 (55.8)

 Parenchyma atrophy (%)

  Negative

63 (63.0)

20 (46.5)

  Positive

37 (37.0)

23 (53.5)

 Pancreatic duct expansion (%)

  Negative

32 (32.0)

17 (39.5)

  Positive

68 (68.0)

26 (60.5)

 Vessels invasion (%)

  Negative

72 (72.0)

32 (74.4)

  Positive

28 (28.0)

11 (25.6)

 Extrapancreatic perineural invasion status (%)

  Negative

33 (33.0)

12 (27.9)

  Positive

67 (67.0)

31 (72.1)

DECT quantitative parameters

 NIC of AP

0.09 ± 0.04

0.08 ± 0.03

 NZeff of AP

0.68 ± 0.04

0.68 ± 0.05

 λHU of AP

1.37 ± 0.52

1.22 ± 0.50

 NIC of PVP

0.38 ± 0.11

0.37 ± 0.07

 NZeff of PVP

0.87 ± 0.05

0.86 ± 0.03

 λHU of PVP

2.30 ± 0.70

2.09 ± 0.54

 ECVf (%*)

36.08 ± 6.52

35.18 ± 6.69

  1. The % value reflects the composition ratio
  2. The %* value reflects the percentages
  3. AP arterial phase, DECT dual-energy computed tomography, ECVf the extracellular volume fraction, LN lymph node, NIC normalized iodine concentration, NZeff normalized effective atomic number, PVP portal venous phase, SD standard deviation, λHU slope of the spectral Hounsfield unit curve