Fig. 10
From: MRI characteristics of chemotherapy-related central neurotoxicity: a pictorial review
MRI characteristics of limbic encephalitis. a A 53-year-old male, presenting with headache and drowsiness, tested positive for Leucine-rich, glioma inactivated 1 (LGI1) antibody. MRI depicted symmetrical FLAIR (a1, a2) and T2 (a3) signal abnormalities in bilateral medial temporal lobes. No enhancement was observed in the T1 post-contrast sequence (a4). b Comparative case: highlighting a case of herpes encephalitis, a primary differential for autoimmune limbic encephalitis. A 36-year-old man diagnosed with herpes simplex encephalitis displayed involvement of the right medial temporal lobes and bilateral insular cortices, more severe on the right side, showcasing elevated FLAIR (axial b1 and coronal b3) and T2 (b2) signal intensities. Blooming artifacts in the right medial temporal lobe on SWI sequence (b4) suggested hemorrhage, favoring herpes simplex encephalitis over autoimmune encephalitis