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Insights into Imaging

Table 2 Comparison of spectral quantitative parameters between mesenteric adipose tissue in the controls, “normal” mesenteric adipose tissue with Crohn’s disease, and creeping fat with Crohn’s disease

From: CT energy spectral parameters of creeping fat in Crohn’s disease and correlation with inflammatory activity

Quantitative parameter

Controls (n = 40)

“Normal” MAT with CD (n = 40)

Creeping fat with CD (n = 40)

p value*

p value**

p value***

λHU (HU/keV) at the enteric phase

 − 1.33 (− 1.58 to − 1.24)

 − 1.22 (− 1.40 to − 1.00)

0.58 (− 0.05 to 1.20)

 < 0.001

 < 0.001

0.135

NFIC at the enteric phase

1.00 (1.00–1.01)

1.00 (1.00–1.005)

1.05 (1.02–1.07)

 < 0.001

 < 0.001

1.000

NFWC at the enteric phase

0.83 (0.72–0.94)

0.89 (0.76–0.99)

 − 0.41 (− 0.92 to − 0.46)

 < 0.001

 < 0.001

1.000

NFVF at the enteric phase

1.00 (0.99–1.02)

1.00 (0.98–1.08)

0.33 (0.26–0.79)

 < 0.001

 < 0.001

1.000

  1. *Comparisons between “normal” MAT with CD and creeping fat with CD
  2. **Comparisons between MAT in the controls and creeping fat with CD
  3. ***Comparisons between MAT in the controls and “normal” MAT with CD
  4. CD, Crohn’s disease; λHU, slope of the spectral Hounsfield unit curve; MAT, mesenteric adipose tissue; NFIC, normalised fat-iodine concentration; NFWC, normalised fat–water concentration; HU, Hounsfield unit; NFVF, normalised fat volume fraction
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