Fig. 2
A 30-year-old male patient with inactive Crohn’s disease and non-stricturing and non-penetrating behaviours (a–g). The enteric phase CT enterography axial 70 keV virtual monochromatic (VMC) image (a) demonstrated the thickening of the ileal bowel wall as well as creeping fat, and the ROIs were selected in the creeping fat (ROI 1), the normal subcutaneous fat (ROI 2), and the “normal” mesenteric adipose tissue (ROI 3). b showed that compared with the subcutaneous fat (ROI 2) and “normal” mesenteric adipose tissue (ROI 3), the λHU curve of creeping fat (ROI 1) was inverted. c, d, and e showed fat–water material basis images, fat-iodine material basis images, and fat volume fraction maps at the enteric phase, respectively. The resected specimen (f) showed creeping fat wrapping around the affected ileal bowel loop. Pathological image (g) (HE, × 100) showed hyperplasia with increased small round adipocytes, vascular proliferation, and stromal cell infiltration in creeping fat