Table 3 Region-based diagnostic indices for MRI, CT, and [18F]FDG-PET-CT in detecting lymph node metastases based on original and imputed data
Modality | Region | Prev. LNM | Sensitivity | Specificity | PPV | NPV | AUCa |
|---|---|---|---|---|---|---|---|
Original data | |||||||
MRI | Pelvic | 19 (16–21) | 33 (30–36) | 93 (92–95) | 53 (50–56) | 86 (84–88) | 0.631 (0.599–0.663) |
Common iliac | 4 (3–5) | 10 (8–12) | 99 (99–100) | 44 (41–48) | 96 (95–98) | 0.549 (0.500–0.597) | |
CT | Pelvic | 23 (20–27) | 32 (28–36) | 92 (90–94) | 54 (50–58) | 82 (79–85) | 0.620 (0.578–0.661) |
Common iliac | 4 (2–6) | 0 (–) | 99 (99–100) | 0 (–) | 96 (94–98) | 0.497 (0.493–0.500) | |
[18F]FDG-PET-CT | Pelvic | 42 (34–51) | 70 (62–77) | 80 (73–87) | 80 (73–87) | 72 (65–80) | 0.750 (0.674–0.825) |
Common iliac | 16 (9–23) | 19 (11–26) | 98 (95–100) | 60 (50–69) | 87 (80–93) | 0.582 (0.482–0.682) | |
Imputed data | |||||||
MRI | Pelvic | 23 (21–25) | 47 (45–50) | 93 (91–94) | 66 (63–68) | 85 (84–87) | 0.705 (0.675–0.736) |
Common iliac | 8 (7–9) | 12 (10–13) | 99 (99–100) | 56 (53–58) | 93 (92–94) | 0.554 (0.508–0.600) | |
CT | Pelvic | 25 (22–28) | 37 (34–41) | 93 (91–95) | 64 (61–67) | 81 (79–84) | 0.656 (0.615–0.697) |
Common iliac | 8 (7–10) | 4 (3–5) | 99 (99–100) | 33 (30–36) | 92 (90–94) | 0.517 (0.487–0.547) | |
[18F]FDG-PET-CT | Pelvic | 45 (40–50) | 77 (73–82) | 80 (76–84) | 76 (72–80) | 81 (77–85) | 0.803 (0.725–0.881) |
Common iliac | 22 (18–26) | 20 (16–24) | 95 (92–97) | 51 (46–56) | 81 (77–85) | 0.575 (0.489–0.661) | |