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Table 2 Patient-based diagnostic indices for MRI, CT, and [18F]FDG-PET-CT in detecting lymph node metastases based on original and imputed data

From: Diagnostic accuracy of MRI, CT, and [18F]FDG-PET-CT in detecting lymph node metastases in clinically early-stage cervical cancer — a nationwide Dutch cohort study

Modality

Prev LNM

Sensitivity

Specificity

PPV

NPV

AUCa

Original data

 MRI

19 (17–22)

34 (31–36)

93 (92–94)

54 (52–57)

85 (83–87)

0.639 (0.607–0.670)

 CT

24 (21–28)

37 (33–41)

91 (89–93)

57 (53–61)

82 (79–85)

0.646 (0.603–0.688)

 [18F]FDG-PET-CT

44 (35–52)

73 (66–81)

77 (70–84)

71 (63–79)

79 (72–86)

0.787 (0.714–0.860)

Imputed data

 MRI

24 (22–26)

48 (45–50)

92 (91–94)

66 (64–69)

85 (83–87)

0.706 (0.674–0.737)

 CT

26 (23–29)

40 (37–43)

92 (91–94)

64 (61–67)

82 (79–84)

0.667 (0.630–0.704)

 [18F]FDG-PET-CT

46 (41–51)

80 (76–84)

79 (75–83)

76 (72–81)

82 (78–86)

0.814 (0.752–0.876)

  1. Numbers represent % with (95% confidence interval)
  2. Abbreviation: Prev LNM prevalence of lymph node metastases
  3. aAUC without dichotomising the nodal status on imaging