Model | Intratumoral model | Peritumoral model | Combined model | Clinical model | Intratumoral-clinical model | Peritumoral-clinical model | Combined-clinical model |
---|---|---|---|---|---|---|---|
Training group | |||||||
 AUC | 0.943 | 0.846 | 0.949 | 0.756 | 0.955 | 0.898 | 0.960 |
 95% CI | 0.896–0.974 | 0.781–0.898 | 0.903–0.978 | 0.682–0.820 | 0.910–0.981 | 0.840–0.940 | 0.917–0.984 |
 p value |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
 ACC (%) | 89.44 | 74.53 | 90.06 | 73.91 | 93.79 | 83.85 | 91.93 |
 SEN(%) | 86.73 | 63.27 | 93.88 | 81.63 | 93.88 | 86.73 | 93.88 |
 SPE(%) | 93.65 | 92.06 | 84.13 | 61.90 | 93.65 | 79.37 | 88.89 |
 PPV(%) | 95.51 | 92.54 | 90.20 | 76.92 | 95.83 | 86.73 | 92.93 |
 NPV(%) | 81.94 | 61.70 | 89.83 | 68.42 | 90.77 | 79.37 | 90.32 |
Validation group | |||||||
 AUC | 0.778 | 0.701 | 0.815 | 0.672 | 0.808 | 0.759 | 0.843 |
 95% CI | 0.663–0.869 | 0.579–0.804 | 0.705–0.898 | 0.549–0.779 | 0.696–0.892 | 0.641–0.853 | 0.736–0.919 |
 p value |  < 0.0001 | 0.002 |  < 0.0001 | 0.0093 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
 ACC (%) | 75.71 | 70.00 | 82.86 | 62.86 | 74.29 | 77.14 | 81.43 |
 SEN(%) | 78.57 | 80.95 | 95.24 | 57.14 | 69.05 | 83.33 | 80.95 |
 SPE(%) | 71.43 | 53.57 | 64.29 | 71.43 | 82.14 | 67.86 | 82.14 |
 PPV(%) | 80.49 | 72.34 | 80.00 | 75.00 | 85.29 | 79.55 | 87.18 |
 NPV(%) | 68.97 | 65.22 | 90.00 | 52.63 | 63.89 | 73.08 | 74.19 |