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Table 1 Comparison of clinical, pathological and imaging parameters between training and validation groups

From: Intratumoral and peritumoral radiomics predict pathological response after neoadjuvant chemotherapy against advanced gastric cancer

 

Training group

p value

Validation group

p value

GR (63)

PR (98)

GR (28)

PR (42)

Gender

  

0.471a

  

0.062a

 Male

53

78

 

17

34

 

 Female

10

20

 

11

8

 

Age (years)

58.00 (52.00, 66.00)

62.00 (56.00, 69.00)

0.031b

61.00 (57.00, 65.75)

63.00 (58.00, 67.25)

0.387b

Tumor location

  

0.113c

  

0.079c

 Fundus

42

60

 

18

26

 

 Body

10

27

 

2

11

 

 Antrum

11

9

 

7

4

 

 ≥ 2/3

0

2

 

1

1

 

Borrmann

  

0.031c

  

0.907c

 I

3

5

 

2

4

 

 II

50

60

 

22

29

 

 III

10

33

 

4

8

 

 IV

0

0

 

0

1

 

Clinical T stage

  

0.688a

  

0.492c

 2

6

7

 

4

3

 

 3

43

64

 

16

29

 

 ≥ 4a

14

27

 

8

10

 

Clinical N stage

  

0.437a

  

0.411a

 N0

27

36

 

8

16

 

 N + 

36

62

 

20

26

 

Thickness (mm)

13.82 (9.88, 16.16)

13.02 (10.08, 16.47)

0.609b

13.78 (11.03, 16.33)

13.16 (10.48, 16.87)

0.971b

Histopathology

  

0.091a

  

0.552a

 Adenocarcinoma

55

75

 

23

32

 

 Non-adenocarcinoma

8

23

 

5

10

 

Differentiation

  

0.102c

  

0.146a

 Well

1

0

 

0

0

 

 Moderate

38

48

 

12

11

 

 Poor

24

50

 

16

31

 

Lauren

  

0.001a

  

0.117a

 Intestinal type

44

41

 

17

15

 

 Mixed type

6

27

 

6

16

 

 Diffuse type

13

30

 

5

11

 

CEA

  

0.069a

  

0.188a

 Normal

49

63

 

18

33

 

 Elevated

14

35

 

10

9

 

CA125

  

0.942

  

0.383

 Normal

57

89

 

25

40

 

 Elevated

6

9

 

3

2

 

CA199

  

0.657

  

0.714

 Normal

51

82

 

23

33

 

 Elevated

12

16

 

5

9

 
  1. GR Good response, PR Poor response, CEA Carcinoembryonic antigen, CA125 Carbohydrate antigen 125, CA199 Carbohydrate antigen 199
  2. aχ2 value
  3. bZ value
  4. cFisher’s exact probability method