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Table 1 Overview of existing international guidelines with regard to surveillance imaging after the initial (3–6 months) post-treatment baseline imaging study

From: Post-treatment surveillance imaging in head and neck cancer: a systematic review

Organization

Year

Guidelines

NCCN [8]

2022

• Imaging only in locoregionally advanced disease and only if clinically indicated

• PET-CT may be the most sensitive imaging modality

• If a PET/CT at 3 months post-treatment is negative, there are no data to support substantial benefit for further routine imaging in an asymptomatic patient with negative clinical exam

• Routine annual imaging (repeat use of pretreatment imaging modality) may be indicated to visualize areas inaccessible to routine clinical examination (deep-seated anatomic locations or areas obscured by extensive treatment change)

eviCore 2.1 Clinical Guidelines [10]

2021

• No imaging surveillance after first post-treatment scan

• Exceptions: in case of nasopharyngeal primary site or physical exam unable to visualize deep-seated primary site: annual CT or MRI for 3 years

• In smokers: CT chest only if lung cancer screening criteria are met

AWMF (Germany) [11]

2012

• Imaging every 6 months in the first and second year, every 12 months in years 3–5

BAHNO (UK) [12]

2001

• None (symptom-directed only)

EHNS-ESMO-ESTRO [15]

 

• Imaging should be carried out if symptoms occur or in cases of abnormalities found at the clinical examination

ASCO [13]

2019

• Only if initial PET-CT shows possibly suspect lymph node

AHNS [16]

2016

• Consider in case of smoking history, nasopharyngeal primary, or tumor site inaccessible to clinical examination

• Endorses NCCN guidelines

NI-RADS [17]

2018

• CT, MRI, or PET-CT every 3, 6, or 12 months depending on initial post-treatment imaging findings

ACS [14]

2016

• No definite recommendations