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Table 5 Comparison of the diagnostic performance between the CEUS-predominant and CECT-predominant models

From: Comparison contrast-enhanced CT with contrast-enhanced US in diagnosing combined hepatocellular-cholangiocarcinoma: a propensity score-matched study

 

The CEUS-predominant model

The CECT-predominant model

p value#

Total

 Sensitivity (%)

55.6

93.3

< 0.001

 Specificity (%)

80.0

63.3

0.020

 Accuracy (%)

71.9

73.3

0.583

 AUC (95% CI)a

0.720 (0.632, 0.808)

0.874 (0.816, 0.931)

0.001

≤ 5 (cm)

 Sensitivity (%)

50.0

88.5

0.006

 Specificity (%)

92.0

70.0

0.013

 Accuracy (%)

77.6

76.3

1.000

 AUC (95% CI)

0.710 (0.595, 0.808)

0.792 (0.684, 0.877)

0.226

> 5 (cm)

 Sensitivity (%)

63.2

100

0.016

 Specificity (%)

65.0

55.0

0.503

 Accuracy (%)

64.4

69.5

0.557

 AUC (95% CI)

0.641 (0.505, 0.762)

0.775 (0.648, 0.873)

0.093

  1. CEUS contrast-enhanced ultrasound, CECT contrast-enhanced computed tomography, AUC area under the curve, CI confidence interval
  2. aThe discrimination of AUC value was considered fair (AUC < 0.6), moderate (AUC, 0.6-0.75), and substantial (AUC > 0.75), respectively
  3. #p value was obtained from the comparison between the CEUS-predominant and CECT-predominant models by the McNemar test. p < 0.05 was considered to indicate a statistical difference