From: Correlation analysis of MR elastography and Ki-67 expression in intrahepatic cholangiocarcinoma
Variable | High Ki-67 (n = 57) | Low Ki-67 (n = 40) | p | |
---|---|---|---|---|
Largest diameter (cm)a | 5.74 ± 2.37 | 5.61 ± 2.16 | 5.91 ± 2.65 | 0.544 |
Location left/right/left + right/caudal lobe | 43 (44.3%)/45 (46.4%)/7 (7.2%)/2 (2.1%) | 26 (45.5%)/27 (47.4%)/3 (5.3%)/1 (1.8%) | 17 (42.5%)/18 (45%)/4 (10.0%)/1 (2.5%) | 0.830 |
Tumor margin Well-defined/ill-defined | 69 (71.1%)/28 (28.9%) | 42 (73.7%)/15 (26.3%) | 27 (67.5%)/13 (32.5%) | 0.508 |
Signal homogeneity Homogeneous/heterogeneous | 24 (24.7%)/73 (75.3%) | 14 (24.6%)/43 (75.4%) | 10 (25.0%)/30 (75.0%) | 0.961 |
Arterial enhancement Global/partial/peripheral enhancement | 5 (5.2%)/15 (15.5%)/77 (79.4%) | 1 (1.8%)/6 (10.5%)/50 (87.7%) | 4 (10.0%)/9 (22.5%)/27 (67.5%) | 0.036* |
Enhancement pattern Progressive/persistent/degressive-washout | 84 (86.6%)/4 (4.1%)/9 (9.3%) | 51 (89.5%)/3 (5.3%)/3 (5.3%) | 33 (82.5%)/1 (2.5%)/6 (15.0%) | 0.295 |
APHE Y/N | 75 (77.3%)/22 (22.7%) | 45 (78.9%)/12 (21.1%) | 30 (75.0%)/10 (25.0%) | 0.648 |
Capsule Y/N | 20 (20.6%)/77 (79.4%) | 15 (26.3%)/42 (73.7%) | 5 (12.5%)/35 (87.5%) | 0.098 |
Targetoid appearance Y/N | 76 (78.4%)/21 (21.6%) | 50 (87.7%)/7 (12.3%) | 26 (65.0%)/14 (35.0%) | 0.007* |
Satellite nodules Y/N | 29 (29.9%)/68 (70.1%) | 16(28.1%)/41 (71.9%) | 13 (32.5%)/27 (67.5%) | 0.639 |
Bile duct dilation Y/N | 61 (62.9%)/36 (37.1%) | 34 (59.6%)/23 (40.4%) | 27 (67.5%)/13 (32.5%) | 0.431 |
Liver capsule retraction Y/N | 37 (38.1%)/60 (61.9%) | 22 (38.6%)/35 (61.4%) | 15 (37.5%)/25 (62.5%) | 0.913 |
Hemorrhage in mass Y/N | 4 (4.1%)/93 (95.9%) | 2 (3.5%)/55 (96.5%) | 2(5.0%)/38 (95.0%) | 1.000 |
Necrotic or cystic portion Y/N | 36 (37.1%)/61 (62.9%) | 22 (38.6%)/35 (61.4%) | 14 (35.0%)/26 (65.0%) | 0.718 |
Central scar Y/N | 48 (49.5%)/49 (50.5%) | 29 (50.9%)/28 (49.1%) | 19 (47.5%)/21 (52.5%) | 0.743 |
Central darkness on T2WI Y/N | 45 (46.4%)/52 (53.6%) | 27(47.4%)/30 (52.6%) | 18 (45.0%)/22 (55.0%) | 0.818 |
Vessel invasion Y/N | 76 (78.4%)/21 (21.6%) | 46 (80.7%)/11 (19.3%) | 30 (75.0%)10/ (25.0%) | 0.502 |
Lymphadenectasis Y/N | 42 (43.3%)/55 (56.7%) | 23 (40.4%)/34 (59.6%) | 19 (47.5%)/21 (52.5%) | 0.484 |
Distant metastasis Y/N | 11 (11.3%)/86 (88.7%) | 8 (14.0%)/49 (86.0%) | 3 (7.5%)/37 (92.5%) | 0.517 |
Tumor ADC (× 103 mm2/s)b | 1.13 (0.96, 1.30) | 1.02 (0.87, 1.22) | 1.19 (1.06, 1.42) | < 0.001* |
Tumor stiffness (kPa)b | 7.94 (6.23, 11.09) | 10.16 (7.17, 12.04) | 6.37 (5.65, 7.69) | < 0.001* |
Liver stiffness (kPa)b | 2.74 (2.30, 3.52) | 2.65 (2.30, 3.64) | 2.77 (2.31, 3.47) | 0.959 |