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Table 1 Baseline clinical characteristics of the patient

From: Correlation analysis of MR elastography and Ki-67 expression in intrahepatic cholangiocarcinoma

Variable

 

High Ki-67 (n = 57)

Low Ki-67 (n = 40)

p

Age (years)a

62 (52, 66)

63 (51.5, 67)

59.5 (54, 66)

0.615

Sex, male/female

57 (58.8%)/40 (41.2%)

41 (71.9%)/16 (28.1%)

16 (40.0%)/24 (60.0%)

0.002*

AFP ≥ 20/ < 20 ng/mL

9 (9.3%)/88 (90.7%)

6 (10.5%)/51 (89.5%)

3 (7.5%)/37 (92.5%)

0.732

CEA ≥ 5/ < 5 ng/mL

29 (29.9%)/68 (70.1%)

21 (36.8%)/36 (63.2%)

8 (20.0%)/32 (80.0%)

0.074

CA19-9 ≥ 37/ < 37 ng/mL

53 (54.6%)/44 (45.4%)

37 (64.9%)/20 (35.1%)

16 (40.0%)/24 (60.0%)

0.015*

TBil > 20.4/ ≤ 20.4 μmol/L

5 (5.2%)/92 (94.8%)

1 (1.8%)/56 (98.2%)

4 (10.0%)/36 (90.0%)

0.156

ALT > 35/ ≤ 35 U/L

20 (20.6%)/77 (79.4%)

11 (19.3%)/46 (80.7%)

9 (22.5%)/31 (77.5%)

0.701

AST > 40/ ≤ 40 U/L

16 (16.5%)/81 (83.5%)

8 (14.0%)/49 (86.0%)

8 (20.0%)/32 (80.0%)

0.436

ALP > 125/ ≤ 125 U/L

33 (34.0%)/64 (66.0%)

22 (38.6%)/35 (61.4%)

11 (27.5%)/29 (72.5%)

0.256

γGGT > 60/ ≤ 60 U/L

53 (54.6%)/44 (45.4%)

35 (61.4%)/22 (38.6%)

18 (45.0%)/22 (55.0%)

0.110

Chronic liver disease Y/N

29 (29.9%)/68 (70.1%)

17 (29.8%)/40 (70.2%)

12 (30.0%)/28 (70.0%)

0.777

Hepatitis B

26 (89.7%)

16 (94.1%)

10 (83.3%)

 

Hepatitis C

0 (0.0%)

0 (0.0%)

0 (0.0%)

 

Hepatitis B + C

1 (3.4%)

0 (0.0%)

1 (8.3%)

 

Other causes

2 (6.9%)

1 (5.9%)

1 (8.3%)

 

Cirrhosis Y/N

22 (22.7%)/75 (77.3%)

12 (21.1%)/45 (78.9%)

10 (25.0%)/30 (75.0%)

0.648

  1. Unless otherwise indicated, data are numbers of patients
  2. Quantitative variables are analyzed using the Mann–Whitney U-test; categorical variables are analyzed using Pearson’s χ2 test or Fisher’s exact test, as appropriate
  3. AFP alpha fetoprotein, CEA carcinoembryonic antigen, CA19-9 cancer antigen 19–9, TBil total bilirubin, ALT alanine aminotransferase, AST aspartate aminotransaminase, ALP alkaline phosphatase, γGGT γ-glutamyltransferase
  4. aData are median (Q1, Q3)
  5. *Data are statistically significant results