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Insights into Imaging
Fig. 2 | Insights into Imaging

Fig. 2

From: Assessment of lung deformation in patients with idiopathic pulmonary fibrosis with elastic registration technique on pulmonary three-dimensional ultrashort echo time MRI

Fig. 2

The flowchart of elastic registration. a The procedure of inspiratory-to-expiratory imaging registration of transversal lung MRI. The inspiratory and expiratory images of the patient were subjected to isotropic resampling and then the lung and peri-lung regions were extracted as regions of interest (ROI). Based on the ROI only, the inspiratory image is registered to the expiratory image to obtain the registered inspiratory image. b The steps of Jacobian determinant analysis. First, a common space is defined, and the expiratory images of all participants are registered to this common space, and the registration affine matrix of each participant is obtained. Then, based on each participant's affine matrix, a quadratic transformation of the respective Jacobian determinant (JAC) is performed. Finally, participants were grouped, and various comparisons and analyses were made between groups based on the registered JAC

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