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Table 2 Multivariate logistic regression model analysis for the prediction of detecting csPCa by cognitive MRTB in biopsy-naive men

From: Development and validation of a predictive model based on clinical and MpMRI findings to reduce additional systematic prostate biopsy

Characteristic

Level

Clinical model

MRI model

Advanced model

Coefficient

OR (95% CI)

p

Coefficient

OR (95% CI)

p

Coefficient

OR (95% CI)

p

Intercept

 

 − 5.05

 < 0.001

 − 3.51

0.001

–8.38

 < 0.001

Age (years)

 + 10

0.487

1.63 (1.15, 2.30)

0.006

0.83

2.30 (1.42, 3.72)

0.001

PSAD (ng/ml2)

 + 0.05

1.0

2.72 (1.86, 3.98)

 < 0.001

0.83

2.30 (1.44, 3.65)

 < 0.001

PI-RADS score

   

  

 < 0.001

  

 < 0.001

3

 

1

 

1

4

1.44

4.24 (1.48, 12.15)

0.007

1.64

5.17 (1.69, 15.72)

0.004

5

3.92

50.13 (12.67, 198.32)

 < 0.001

3.94

51.58 (11.78, 225.86)

 < 0.001

Zone of IL

TZ

 

 

1

  

1

PZ

1.87

6.52 (2.83, 14.99)

 < 0.001

2.34

9.35 (3.56, 24.56)

 < 0.001

Level of IL

   

  

0.107

  

0.563

Base

 

1

  

1

Mid

0.76

2.14 (0.76, 6.02)

0.149

0.28

1.32 (0.42, 4.14)

0.635

Apex

1.25

3.48 (1.09, 11.04)

0.035

0.67

1.95 (0.54, 7.04)

0.307

MD of IL (cm)

   

  

0.831

 < 0.8

 

1

0.8–1.4

0.112

1.12 (0.19, 6.54)

0.901

 ≥ 1.5

–0.19

0.827 (0.124, 5.50)

0.845

  1. CI confidential interval, IL index lesion, MD maximum diameter, OR odds ratio, PI-RADS Prostate Imaging Reporting and Data System, PSAD prostate-specific antigen density