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Table 1 Demographic characteristics and hemodynamics of patients in the modeling group according to mean pulmonary artery pressure

From: Cardiovascular metrics on CT pulmonary angiography in patients with pulmonary hypertension — re-evaluation under the updated guidelines of pulmonary hypertension

Characteristics

Group A

(mPAP ≤ 20 mmHg)

Group B (25 mmHg > mPAP > 20 mmHg)

Group C

(mPAP ≥ 25 mmHg)

p value

A and B

A and C

B and C

Case number (%)

62 (28.4%)

34 (15.6%)

122 (56%)

    

Age (years)

52.1 ± 12.6

57.9 ± 14.0

56.3 ± 11.3

0.035

0.026

0.025

0.513

Gender (male/female)

29/33

18/16

56/66

0.57

0.979

0.404

0.467

BMI (kg/m2)

24.9 ± 3.5

25.5 ± 4.5

24.3 ± 3.2

0.227

0.585

0.053

0.141

BSA (m2)

1.76 ± 0.19

1.76 ± 0.18

1.70 ± 0.18

0.075

0.975

0.043

0.149

SBP (mmHg)

133.2 ± 20.3

129.9 ± 18.3

130.5 ± 19.8

0.717

0.549

0.448

0.902

DBP (mmHg)

81.3 ± 12.7

80.3 ± 11.5

83.9 ± 13.9

0.386

0.799

0.269

0.296

NT-proBNP (pg/mL)

54 (20–83)

70 (38.8–121.5)

519 (179–1284)

 < 0.001*

0.377

 < 0.001*

 < 0.001*

Heart rate (bpm)

70 ± 11

66 ± 7

74 ± 13

0.03

0.239

0.106

0.016

6MWD (m)

530 (442–580)

472.0 (430–533.5)

393.5 (300–460)

 < 0.001*

0.614

 < 0.001*

 < 0.001*

Hemodynamics

 MPA SO%

74.2 ± 6.4

71.6 ± 3.8

65.8 ± 9.8

 < 0.001*

0.412

0.009

0.004

 Aorta SO%

99.4 ± 1.3

98.9 ± 2.0

98.3 ± 2.8

0.03

0.412

0.009

0.317

 mPAP (mmHg)

15.2 ± 3.2

22.9 ± 1.1

40.6 ± 10.6

 < 0.001*

 < 0.001*

 < 0.001*

 < 0.001*

 mRAP (mmHg)

2 (0.8–4)

3 (1–5)

5 (2–7)

 < 0.001*

0.032

 < 0.001*

0.062

 mRVP (mmHg)

9.5 (8–12)

14 (12–17)

26 (21–31)

 < 0.001*

0.017

 < 0.001*

 < 0.001*

 PAWP (mmHg)

9.2 ± 3

11.1 ± 2.3

9.4 ± 2.8

0.017

0.008

0.76

0.007

 PVR (Wood U)

1.3 (0.7–1.8)

2.6 (2.0–2.8)

9.6 (6.3–13.8)

 < 0.001*

0.033

 < 0.001*

 < 0.001*

 CO (L/min)

4.6 ± 1.3

3.9 ± 0.7

3.3 ± 1.0

 < 0.001*

0.012

 < 0.001*

0.025

 CI (L/min/m2)

2.6 ± 0.7

2 .2 ± 0.4

2.0 ± 0.6

 < 0.001*

0.009

 < 0.001*

0.04

Diagnosis

 CPE

55

34

113

    

 Takayasu arteritis

4

      

 Fibrosing mediastinitis

2

      

 Behcet syndrome

1

      

 IPAH

  

5

    

 PVOD

  

3

    

 PCH

  

1

    
  1. CTEPH Chronic thromboembolic pulmonary hypertension, BMI Body mass index, NT-proBNP N-terminal-pro-B-type natriuretic peptide, 6MWD 6-min walking distance, NYHA FC New York Heart Association classification functional class, mPAP mean pulmonary arterial pressure, mRAP mean right atrial pressure, PAWP Pulmonary artery wedge pressure, SBP Systolic blood pressure, DBP Diastolic blood pressure, PVR Pulmonary vascular resistance, CO Cardiac output, CI Cardiac index, CPE Chronic pulmonary embolism, IPAH Idiopathic pulmonary hypertension, PVOD Pulmonary veno-occlusive disease, PCH Pulmonary capillary hemangiomatosis
  2. *p < 0.001