Early chest CT abnormalities to predict the subsequent occurrence of chronic lung allograft dysfunction

Insights into Imaging

Table 3 Multivariate analysis for the occurrence of CLAD and death

	Parameters	p-value	HR	CI 95%
Multivariate analysis for CLAD
Clinical	Age at LTx	0.76	1.0	0.9–1.1
	Gender	0.14	2.2	0.8–6.1
	Etiology for LTx	0.40
CTi	Moderate arterial anastomosis stenosis	0.01	4.5	1.6–13.2
CTf	Consolidations (> 4 segments)	0.002	2.9	1.2–7.4
CTf	Pleural effusion	0.01	2.8	1.5–5.4
Multivariate analysis for death
Clinical	Age at LTx	0.96	1.00	0.9–1.1
CTf	Pleural effusions	< 0.001	9.8	2.7–35.7
CTf	Consolidations (1–3 segments)	0.01	8.2	1.5–43.3

CLAD Chronic lung allograft disease, CT Computed tomography, LTx Lung transplantation, RAS restrictive allograft syndrome