Early chest CT abnormalities to predict the subsequent occurrence of chronic lung allograft dysfunction

Insights into Imaging

Table 2 Clinical characteristics of the study population

	N = 118
Age at LTx (years)	47 [18–68]
Recipient gender (male)	63 (53.4%)
Recipient size (m)	1.66 [1.46–1.87]
Theoretical recipient TLC (L)	5.79 [3.85–7.86]
Bi-pulmonary transplantation	91 (77.1%)
Mono-pulmonary transplantation	27 (22.9%)
Graft ischemic time (min)	327 [16–694]
Donor PaO₂/FiO₂	417 [217/604]
Donor gender (male)	65 (55.1%)
Donor size (m)	1.70 [1.52–1.92]
Theoretical donor TLC (L)	6.4 [3.1–8.3]
Recipient TLC before LTx (%)	103.4 [38.7–218.3]
FEV₁ baseline (L)	2.5 [1.0, 4.9]
Ratio theoretical TLC donor/recipient	1.06 [0.62–1.90]
Etiology for LTx
Emphysema	35 (29.7%)
Fibrosis	28 (23.7%)
Cystic fibrosis and bronchial dilatations	42 (35.6%)
New LTx for CLAD	6 (5.1%)
Others	7 (5.9%)
Reject type
Stable	93 (78.8%)
CLAD	25 (21.2%)
BOS	19 (16.1%)
RAS	6 (5.1%)
Death	19 (15.7%)
Delay for chest CT after LTx (days)
Initial (CTi)	47 [31–134]
Follow-up (CTf)	381 [298–742]
Follow-up duration (years)	3.9 [1.1–6.5]

Results given as median [min-max] or n (%). BOS Bronchial obstructive syndrome, CLAD Chronic lung allograft disease, CT Computed tomography, LTx Lung transplantation, RAS Restrictive allograft syndrome, TLC Total lung capacity