From: Differentiation of pulmonary solid nodules attached to the pleura detected by thin-section CT
Characteristics | Benign SPANs (n = 128) | Malignant SPANs (n = 172) | p-value |
---|---|---|---|
Distribution | 0.053 | ||
 Upper lobe | 54 (42.2) | 92 (53.5) | |
 Middle and lower lobes | 74 (57.8) | 80 (46.5) | |
Abutting the mediastinal pleura | 10 (7.8) | 43 (25.0) |  < 0.001 |
Size (mm) | 14.55 ± 6.84 | 19.18 ± 6.07 |  < 0.001 |
Shape (irregular) | 8 (6.3) | 9 (5.2) | 0.706 |
Lobulation | 23 (18.0) | 128 (74.4) |  < 0.001 |
Spiculation | 25 (19.5) | 77 (44.8) |  < 0.001 |
Narrow basement | 65 (50.8) | 137 (79.7) |  < 0.001 |
Adjacent pleural change | 0.229 | ||
 No | 101 (78.9) | 144 (83.7) | |
 Pleural thickening | 27 (21.1) | 28 (16.3) | |
R-thickening | 1.31 ± 0.68 | 0.75 ± 0.27 |  < 0.001* |
Extrapleural fat thickening | 14 (10.9) | 24 (14.0) | 0.437 |
Relationship between nodule and pleura |  < 0.001 | ||
 Type I | 99 (77.3) | 126 (73.3) | 0.419 |
 Type II | 12 (9.4) | 24 (13.4) | 0.145 |
 Type III | 15 (11.7) | 3 (1.7) |  < 0.001 |
 Type IV | 2 (1.6) | 20 (11.6) | 0.001 |
Concomitant lesions in peripheral lung fields (yes) | 51 (39.8) | 43 (25.0) | 0.006 |
Lymph node enlargement | 0.002 | ||
 No | 112 (87.5) | 122 (70.9) | 0.001 |
 Hilar or mediastinal lymph nodule enlargement | 9 (7.0) | 24 (14.0) | 0.058 |
 Simultaneous hilar and mediastinal lymph nodule enlargement | 7 (5.5) | 26 (15.1) | 0.008 |
Plain CT value (HU) | 37.17 ± 30.0 | 33.06 ± 17.67 | 0.802 |
△CT value (HU) | 45.85 ± 23.50 | 42.05 ± 19.17 | 0.463* |