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Insights into Imaging

Table 4 Comparison of predictive efficacy for PHLF between the model and ALBI score

From: CT-derived extracellular volume and liver volumetry can predict posthepatectomy liver failure in hepatocellular carcinoma

 

Training cohort

Internal validation cohort

External validation cohort

Model

ALBI score

Model

ALBI score

Model

ALBI score

AUC (95% CI)

0.861 (0.802–0.908)

0.616 (0.541–0.687)

0.965 (0.907–0.991)

0.711 (0.611–0.797)

0.971 (0.921–0.994)

0.662 (0.566 − 0.748)

Youden index

0.650

0.207

0.832

0.486

0.869

0.256

Cutoff value

0.325

 − 2.383

0.232

 − 2.257

0.179

 − 2.606

Sensitivity

0.831

0.431

0.931

0.655

0.969

0.469

Specificity

0.819

0.776

0.901

0.831

0.900

0.788

p valuea

 < 0.001

 

 < 0.001

 

 < 0.001

 
  1. Note: Cutoff values were chosen to achieve the Youden index. p value < 0.05 means significant
  2. Abbreviations: AUC Area under the receiver operating characteristic, CI Confidence interval, ALBI Albumin–bilirubin, PHLF Posthepatectomy liver failure
  3. aThe significance of the differences between the model and the ALBI score was assessed by the DeLong test
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