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Table 3 Predictive efficacy of DLCT quantitative parameters for MSI status of GC in the training set

From: Dual-layer spectral-detector CT for predicting microsatellite instability status and prognosis in locally advanced gastric cancer

Parameters

Threshold

AUC (95% CI)

Sensitivity (%)

Specificity (%)

Accuracy (%)

CT40keV_VP, HU

154.30

0.620 (0.525, 0.715)

62.75 (32/51)

66.92 (89/133)

65.76 (121/184)

CT70keV_VP, HU

84.82

0.601 (0.510, 0.691)

66.67 (34/51)

54.89 (73/133)

58.15 (107/184)

IDVP, mg/ml

1.32

0.773 (0.690, 0.855)

74.51 (38/51)

78.20 (104/133)

77.17 (142/184)

NIDVP

0.29

0.802 (0.734, 0.870)

78.43 (40/51)

71.43 (95/133)

73.37 (135/184)

ZeffVP

8.00

0.795 (0.709, 0.882)

78.43 (40/51)

84.21 (112/133)

82.61 (152/184)

λHUVP

1.66

0.797 (0.714, 0.880)

72.55 (37/51)

81.20 (108/133)

78.80 (145/184)

  1. Except for AUC, values are percentage with number of examinations in parentheses
  2. AUC Area under the curve, CI Confidence interval, DLCT Dual-layer spectral detector CT, GC Gastric cancer, ID Iodine density, λHU The slope of the spectral curve, MSI Microsatellite instability, NID Normalized iodine density, VP Venous phase, Zeff Effective atomic number