Skip to main content
Insights into Imaging

Table 1 Clinicopathological data of gastric cancer patients in training set and validation set

From: Dual-layer spectral-detector CT for predicting microsatellite instability status and prognosis in locally advanced gastric cancer

Variables

Training set (n = 184)

Validation set (n = 80)

p value†

MSI-H (n = 51)

MSI-L/MSS (n = 133)

p value*

MSI-H (n = 19)

MSI-L/MSS (n = 61)

p value*

 

Age, years

63.24 ± 8.95

58.73 ± 11.20

0.011

63.37 ± 5.57

57.15 ± 10.70

0.018

0.340

Gender

  

0.367

  

0.366

0.492

 Male

38

90

 

12

47

  

 Female

13

43

 

7

14

  

CEA

  

0.639

  

1.000

0.188

 Normal

44

1

 

15

47

  

 Elevated

7

22

 

4

14

  

CA19-9

  

0.870

  

0.797

0.169

 Normal

46

121

 

17

51

  

 Elevated

5

12

 

2

10

  

MD, cm

4.43 ± 1.79

4.62 ± 1.63

0.498

4.07 ± 1.17

4.68 ± 1.72

0.154

0.860

MT, cm

2.04 ± 0.45

2.03 ± 0.45

0.931

2.23 ± 0.59

2.08 ± 0.42

0.223

0.182

Tumor location

  

 < 0.001

  

0.026

0.367

 Cardia/fundus

9

45

 

4

19

  

 Corpus

12

55

 

2

21

  

 Antrum/pylorus

30

33

 

13

21

  

CT_T staging

  

0.046

  

0.017

0.443

 T2

15

26

 

7

7

  

 T3

22

44

 

7

19

  

 T4a

14

63

 

5

35

  

CT_N staging

  

 < 0.001

  

0.003

0.976

 N0

15

9

 

6

6

  

 N1

22

36

 

9

15

  

 N2

13

58

 

4

27

  

 N3

1

30

 

0

13

  

cTNM staging (AJCC 8th)

  

0.002

  

0.019

0.525

 I

8

6

 

5

4

  

 II

15

22

 

6

12

  

 III

28

105

 

8

45

  

Histopathological type

  

0.187

  

0.105

0.972

 Adenocarcinoma

36

77

 

12

36

  

 Poorly cohesive

7

38

 

2

18

  

 Mucinous

5

12

 

2

5

  

 Mixed

3

6

 

3

2

  

Histological grade

  

0.468

  

0.149

0.716

 Well

5

9

 

4

4

  

 Moderate

8

30

 

2

12

  

 Poor

38

94

 

13

45

  

Lauren type

  

0.014

  

0.021

0.790

 Intestinal type

32

52

 

13

20

  

 Mixed type

12

46

 

4

24

  

 Diffuse type

7

35

 

2

17

  

Lymphovascular invasion

  

0.272

  

0.771

0.322

 Positive

23

72

 

8

28

  

 Negative

28

61

 

11

33

  

Perineural invasion

  

0.589

  

0.462

0.581

 Positive

20

58

 

6

25

  

 Negative

31

75

 

13

36

  
  1. Data are expressed as mean ± SD or number with percentage in parentheses. Statistically significant results are marked in bold
  2. CA19-9 Carbohydrate antigen 19–9, CEA Carcinoembryonic antigen, DLCT Dual-layer spectral detector CT, MD Maximum diameter, MSI-H Microsatellite instability high, MSI-L/MSS Microsatellite instability low or microsatellite stable, MT Maximum thickness
  3. *Comparison between MSI -H group and MSI-L/MSS group
  4. †Comparison between training set and validation set
Back to article page