Table 3 Pooled sensitivities, specificities, and AUCs for MRI-inclusive and clinical nomograms for predicting EPE (validation cohorts only)
Nomogram | No. of cohorts | No. of patients | Sensitivity (95% CI) | Heterogeneity | Specificity (95% CI) | Heterogeneity | AUC (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|
I 2 (%) | Cochran Q p value | I2 (%) | Cochran Q p value | ||||||
MRI-inclusive nomograms | 13 | 2177 | 0.76 (0.67, 0.83) | 81.18 (71.69, 90.66) |  < 0.001 | 0.71 (0.59, 0.80) | 94.75 (92.92, 96.58) |  < 0.001 | 0.80 (0.76, 0.83) |
Clinical nomograms | 11 | 2437 | 0.68 (0.59, 0.75) | 84.21 (75.93, 92.49) |  < 0.001 | 0.71 (0.64, 0.78) | 88.50 (82.98, 94.02) |  < 0.001 | 0.75 (0.71, 0.79) |
Partin table | 8 | 2105 | 0.73 (0.62, 0.82) | 88.29 (82.57, 95.01) |  < 0.001 | 0.60 (0.47, 0.72) | 93.26 (89.97, 96.56) |  < 0.001 | 0.72 (0.68, 0.76) |
MSKCCn | 5 | 442 | 0.68 (0.60, 0.75) | 26.26 (0, 94.20) | 0.25 | 0.76 (0.70, 0.82) | 28.18 (0, 95.54) | 0.23 | 0.79 (0.75, 0.82) |