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Table 1 Basic characteristics of included study for quantitative analysis (MRI-inclusive nomograms)

From: Diagnostic performance of prediction models for extraprostatic extension in prostate cancer: a systematic review and meta-analysis

Author (publication year)

Study characteristics

Clinical characteristics

MRI characteristics

Country

TRIPOD style

No. of patients

EPE rate

Whole-gland vs. side-specific

Clinical predictors

MRI unit

Tesla

Coil

Slice thichness/gap(mm)

MRI predictor(s)

Alves 2020 [38]

Brazil

4

72

0.46

Whole-gland

biopsy GS

Philips

1.5

Body

ND

ADC, EPE on T2WI, tumor volume

Bai 2021 [39]

China

3

126

0.38

Whole-gland

PSA, biopsy GS

Siemens, GE, UIH

3

Pelvic

3–5/0–1

Peritumoral region radiomics features

Chen 2023 [48]

China

2b

304

0.38

Whole-gland

biopsy GS, number of positive cores

Siemens

3

Body

ND

Largest dimension, EPE

Giganti 2016 [40]

Italy

3

101

0.50

Whole-gland

biopsy GS

Philips

1.5

Endorectal

ND

ADC, EPE on T2WI, tumor volume

Guerra 2022 [49]

Portugal

3

228

0.26

Whole-gland

biopsy GS

Siemens

3

Pelvic

ND

Capsular disruption, CCL, EPE on MRI

Hara 2013 [41]

Tokyo

3

266

0.50

Side-specific

biopsy GS, biopsy cores ≥ 2 and maximum % of positive cores ≥ 31% on either side

Siemens

3

Body

0.73

DWI positivity

He 2021 [42]

China

2a

81

0.50

Whole-gland

biopsy GS, positive core percentage

Siemens

3

Body

3/0

Radiomics features on ADC

Hou 2021 [43]

China

3

849

0.28

Whole-gland

PSA, age, biopsy GS, % of positive cores, biopsy perineural invasion

Siemens

3

Pelvic

3.5

PAGNet model

Lebacle 2016 [44]

France

2a

1743

0.31

Whole-gland

PSA > 5 ng/ml, cT2 or T3, bGS ≥ 7, prostate weigh > 50 g

ND

ND

ND

ND

EPE stage iT3a or iT3b

Majchrzak 2021 [58]

Poland

1a

61

0.22

Side-specific

PSA, biopsy GS, maximum % of positive cores

GE or Siemens

1.5 or 3

ND

ND

EPE on MRI

Soeterik 2020 [29]

The Netherlands

4

550

0.32

Side-specific

PSA, biopsy GS, maximum % of positive cores

ND

ND

ND

ND

EPE on MRI

Wang 2018 [59]

China

1a

541

0.54

Whole-gland

Partin Table 2017

Siemens

3

Pelvic

3.5/0.3

Tumor location, MTD, PIRADS, MR stage

Xiang 2022 [62]

China

1a

105

0.42

Whole-gland

MSKCC

Siemens

1.5

ND

ND

EPE grade

Xu 2020 [45]

China

2a

128

0.38

Per-lesion

PSA, biopsy GS

GE

3

Body

3

Radiomic score

Xu 2021 [60]

China

1a

130

0.48

Whole-gland

PSAD

GE

3

Body

3

EPE grade, PIRADS

Zanelli 2019 [61]

Italy

1a

73

0.33

Whole-gland

Partin2012, MSKCC2004, CAPRA2017

Philips

3

Body

3/0

mpMRI stage

Zapała 2019 [46]

Poland

1b

88

0.30

Side-specific

PSA ≥ 20, % of positive cores ≥ 15%

Philips

1.5

Endorectal

ND

MTD ≥ 15 mm

Zapała 2021 [47]

Poland

4

154

0.23

Side-specific

PSA ≥ 20, % of positive cores ≥ 15%

Philips

3

Non-endorectal

ND

MTD ≥ 15 mm

  1. EPE extraprostatic extension, MTD maximum tumor diameter, GS Gleason Score, mpMRI multiparametric magnetic resonance imaging, cT clinical tumor stage, ND not described, MSKCCn Memorial Sloan Kettering Cancer Center nomogram, CAPRA Cancer of the Prostate Risk Assessment