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Table 1 Population characteristics

From: Best imaging signs identified by radiomics could outperform the model: application to differentiating lung carcinoid tumors from atypical hamartomas

 

Hamartoma training set n = 16

Hamartoma validation set n = 22

p-value$

Carcinoid tumor training set n = 57

Carcinoid tumor validation set n = 32

p-value§

Age (years)

62 [43–76]

58 [50–64]

p = 0.68

58 [41–70]

62 [51–67]

p = 0.28

Gender

 

 Male

10 (62%)

11 (50%)

p = 0.53

10 (25%)

8 (25%)

p = 0.99

 Female

6 (38%)

11 (50%)

47 (75%)

24 (75%)

Type of surgery

 

 Pneumonectomy

0 (0%)

0 (0%)

p = 0.72

2 (3%)

2 (6%)

p = 0.94

 Lobectomy

7 (44%)

1 (5%)

42 (74%)

26 (82%)

 Segmentectomy

0 (0%)

0 (0%)

8 (14%)

2 (6%)

 Wedge resection

7 (44%)

15 (68%)

5 (9%)

2 (6%)

 Enucleation

1 (6%)

6 (27%)

0 (0%)

0 (0%)

 Biopsy

1 (6%)

0 (0%)

0 (0%)

0 (0%)

Diameter (mm)

17 [11–26]

12 [8–18]

p = 0.16

18 [12–26]

18 [13–25]

p = 0.95

Calcifications

7 (44%)

4 (18%)

p = 0.15

9 (16%)

2 (7%)

p = 0.32

Anatomic location

 

 Central

6 (37%)

4 (18%)

p = 0.27

30 (53%)

16 (50%)

p = 0.83

 Peripheral

10 (62%)

18 (82%)

27 (47%)

16 (50%)

Bronchial contact

5 (31%)

5 (23%)

p = 0.71

38 (67%)

25 (78%)

p = 0.33

Endobronchial protrusion

4 (25%)

0 (0%)

p = 0.02

23 (40%)

16 (50%)

p = 0.50

Atelectasis

2 (13%)

0 (0%)

p = 0.17

16 (28%)

12 (38%)

p = 0.48

Borders shape

 

 Smooth

11 (69%)

11 (50%)

p = 0.33

40 (70%)

19 (61%)

p = 0.48

 Lobulated

5 (31%)

11 (50%)

17 (30%)

12 (39%)

Mean 2DROI value (HU)

30 [12–40]

26 [18–33]

p = 0.51

80 [50–103]

78 [57–107]

p = 0.99

Mean 2DROI value (HU) in pulmonary artery trunk

210 [144–283]

225 [186–336]

p = 0.35

229 [183–309]

179 [151–260]

p = 0.03

  1. Demographic and clinical data. Results were expressed in median [Q1-Q3] for quantitative data or number (percentage) for qualitative data. ‘n = ’ corresponds to the number of patients operated. HU—Hounsfield units. A p-value lower than 0.05 was considered as significant. $ Comparison between hamartoma on training and validation set. § Comparison between carcinoids on training and validation set. p-value < 0.05 was highlighted in bold