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Table 1 Basic information and CMR characteristics between patients with and without events

From: Late gadolinium enhancement entropy as a new measure of myocardial tissue heterogeneity for prediction of adverse cardiac events in patients with hypertrophic cardiomyopathy

Characteristics

No events

(n = 294)

Events

(n = 43)

p value

Demographics

Age (y)

51 ± 14

54 ± 15

.196

Male

217 (74)

36 (84)

.161

BMI (kg/m2)

24.9 ± 1.6

25.5 ± 1.1

.001

BSA (m2)

1.8 ± 0.2

1.9 ± 0.1

.107

SBP (mm Hg)

120 ± 9

117 ± 19

.374

DBP (mm Hg)

78 ± 6

77 ± 11

.688

HR (beats/min)

73 ± 9

79 ± 14

.006

Hypertension

57 (19)

12 (28)

.196

Diabetes

27 (9)

4 (9)

.980

CAD

22 (8)

3 (7)

.906

Unexplained syncope

24 (7)

6 (11)

.638

SCD family history

28 (10)

7 (12)

.607

NSVT

19 (7)

5 (9)

.595

NYHA functional class

   

 I

210 (71)

0 (0)

 

 II

31 (11)

8 (19)

 

 III

30 (14)

4 (9)

 

 IV

13 (4)

31 (72)

 

LA diameter (mm)

41.2 ± 7.8

44.8 ± 9.6

.006

Maximal LVWT (mm)

19.5 ± 12.7

18.3 ± 4.4

.522

LVOT gradient pressure (mm Hg)

17.5 ± 12.2

17.1 ± 12.6

.816

CMR parameters

 LVEF (%)

66.3 ± 12.1

43.0 ± 11.8

 < .001

 LVEDVi (ml/m2)

63.1 ± 22.6

89.3 ± 40.5

 < .001

 LVESVi (ml/m2)

34.6 ± 12.6

47.6 ± 21.2

 < .001

 SV (ml)

77.7 ± 49.4

56.5 ± 29.8

.007

 LV mass index (g/ m2)

90.7 ± 41.1

102.8 ± 38.4

.071

 LGE (%)

5.0 ± 5.3

13.9 ± 10.0

 < .001

 LV wall entropy

5.59 ± 0.35

6.20 ± 0.45

 < .001

  1. Data are mean ± SD or n (%)
  2. Events = composite of primary and secondary endpoints
  3. The primary endpoint defined as readmission to the hospital owing to heart failure
  4. The secondary endpoint was the composite of the primary endpoint, sudden cardiac death and non-cardiovascular death