Skip to main content

Table 2 Diagnostic performances in the (a) per-patient and (b) per-lesion analyses

From: Whole-body low-dose CT can be of value in prostate cancer decision-making: a retrospective study on 601 patients

 

Expertise

Sensitivity% (95% CI)

Specificity% (95% CI)

NPV% (95% CI)

PPV% (95% CI)

Accuracy% (95% CI)

TP

TN

FP

FN

(a) Per-patient

All patients

Junior radiologist

83.6 (77.5–88.6)

96.6 (94.4–98.1)

92.8 (90.3–94.7)

91.9 (87.0–95.0)

92.5 (90.1–94.5)

158

398

14

31

Nuclear medicine

81.0 (74.6–86.3)

98.5 (96.9–99.5)

91.9 (89.4–93.8)

96.2 (92.0–98.3)

93.0 (90.7–94.9)

153

406

6

36

Senior radiologist

89.4 (84.1–93.4)

98.5 (96.9–99.5)

95.3 (93.1–96.9)

96.6 (92.7–98.4)

95.7 (93.7–97.2)

169

406

6

20

Patients referred for initial staging

Junior radiologist

78.3 (66.7–87.3)

98.6 (95.0–99.8)

90.3 (85.6–93.6)

96.4 (87.2–99.3)

91.9 (87.4–95.2)

54

140

2

15

Nuclear medicine

76.8 (65.1–86.1)

98.6 (95.0–99.8)

89.7 (85.1–93.1)

96.4 (86.9–99.1)

91.5 (86.9–94.9)

53

140

2

16

Senior radiologist

88.4 (78.4–94.9)

99.3 (96.1–100)

94.6 (90.2–97.1)

98.4 (89.6–99.8)

95.7 (92.1–98.0)

61

141

1

8

Patients referred after biochemical recurrence

Junior radiologist

86.7 (79.3–92.2)

95.6 (92.4–97.7)

94.2 (91.1–96.2)

89.7 (83.2–93.8)

92.8 (89.8–95.2)

104

258

12

16

Nuclear medicine

83.3 (75.4–89.5)

98.5 (96.3–99.6)

93.0 (89.9–95.2)

96.2 (90.4–98.5)

93.9 (91.0–96.0)

100

266

4

20

Senior radiologist

90.0 (83.2–94.7)

98.6 (95.7–99.4)

95.7 (92.7–97.4)

95.6 (90.1–98.1)

95.6 (93.1–97.4)

108

265

5

12

(b) Per-lesion

All lesions

Junior radiologist (n = 518)

51.5 (45.7–57.2)

82.1 (76.1–87.2)

52.1 (48.8–55.4)

81.77 (76.5–88.1)

63.5 (59.1–67.7)

157

161

35

148

Nuclear medicine (n = 427)

48.5 (42.8–54.3)

88.9 (81.0–94.3)

35.9 (33.0–39.0)

93.1 (88.4–96.0)

58.4 (53.4–63.3)

148

88

11

157

Senior radiologist (n = 454)

63.3 (57.6–68.7)

92.1 (86.0–96.2)

51.1 (47.2–55.0)

95.1 (91.3–97.2)

71.8 (67.3–76.0)

193

117

10

112

  1. CI confidence interval, TP true positive, TN true negative, FP false positive, FN false negative