An interpretable MRI-based radiomics model predicting the prognosis of high-intensity focused ultrasound ablation of uterine fibroids

Insights into Imaging

Table 1 Comparison of clinical and radiological characteristics of the training and test sets

Characteristics	Training set (n = 240)		p value	Test set (n = 60)		p value
Characteristics	NPVR ≥ 80% (n = 136)	NPVR < 80% (n = 104)	p value	NPVR ≥ 80% (n = 36)	NPVR < 80% (n = 24)	p value
Age (years)	40 (35, 44)	40 (35, 44)	0.804^a	41.0 ± 6.5	38.4 ± 7.3	0.226^b
Abdominal fat (mm)	14.6 (12.0, 18.6)	16.1 (12.5, 19.9)	0.052^a	16.7 ± 6.4	16.4 ± 6.5	0.844^b
Size (mm)	47.7 (40.5, 56.9)	51.6 (46.7, 61.3)	0.001^a	52.5 ± 10.7	51.1 ± 9.5	0.606^b
Volume (cm³)	55.93 (33.60, 95.71)	71.65 (52.84, 118.59)	0.001^a	68.99 (46.19, 114.30)	71.71 (43.54, 102.96)	0.928^a
Type			< 0.001^c 0.001c			0.027^c
Submucosal	3	3		0	0
Intramural	116	59		32	16
Subserosal	17	42		4	9
T2 signal intensity			< 0.001c			0.067^c
Low intensity	74	55		15	10
Intermediate intensity	27	17		4	8
High intensity	35	32		17	6
T2 signal homogeneity			< 0.001c			0.457^c
Homogeneous	99	57		19	15
Inhomogeneous	37	47		17	9
CE signal homogeneity			0.001^c			0.357^c
Less than myometrium	67	55		21	15
Equivalent to myometrium	51	20		11	4
Greater than myometrium	18	29		4	5
CE signal homogeneity			0.870^c			0.285^c
Homogeneous	47	37		13	12
Inhomogeneous	89	67		23	12

^ap values were obtained by using Wilcoxon rank sum test; ^bp values were obtained by using independent sample t test; ^cp values were obtained by using the Chi-squared test