Robustness of radiomics features of virtual unenhanced and virtual monoenergetic images in dual-energy CT among different imaging platforms and potential role of CT number variability

Insights into Imaging

Table 4 Inter-reproducibility of CT number values

Images	Criteria
Inter-platform reproducibility among all platforms within the VUE images and within the VMI_70keV
16 ROIs	CV < 10%	CV mean	QCD < 10%	QCD mean
VUE	18.75%	1.1389	81.25%	1.4144
VMI_70keV	68.75%	6.8006	87.50%	0.3055
Inter-platform reproducibility between particular platforms within the VUE images and within the VMI_70keV
45 Comparisons	ICC > 0.90	ICC mean	CCC > 0.90	CCC mean
VUE	95.56%	0.9803	95.56%	0.9803
VMI_70keV	100.00%	0.9974	100.00%	0.9972

Percentage indicates the percentage of features met the cutoffs for robustness measures (CV < 10% and QCD < 10%, ICC > 0.90 and CCC > 0.90)