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Table 2 Cox analysis of SyMRI and DWI parameters for the prediction of disease progression in NPC patients

From: Pretreatment synthetic magnetic resonance imaging predicts disease progression in nonmetastatic nasopharyngeal carcinoma after intensity modulation radiation therapy

Parameters

HR (95% CI)

p value

SyMRI

T1_10th

1.001 (0.996, 1.005)

0.825

T1_Mean

0.999 (0.996, 1.002)

0.571

T1_Kurtosis*

1.083 (1.007, 1.165)

0.003

T1_Skewness

1.943 (1.090, 3.465)

0.024

T2_10th

0.929 (0.865, 0.999)

0.047

T2_Mean

0.949 (0.883, 1.019)

0.146

T2_Kurtosis

1.000 (1.000, 1.001)

0.294

T2_Skewness

1.023 (0.978, 1.070)

0.326

PD_10th

0.889 (0.782, 1.011)

0.073

PD_Mean

0.836 (0.717, 0.975)

0.022

PD_Kurtosis

1.127 (0.821, 1.547)

0.460

PD_Skewness

1.111 (0.367, 3.367)

0.852

DWI

ADC

1.006 (1.001, 1.010)

0.002

  1. Parameters in bold mean p < 0.05; *Only T1_Kurtosis was selected to construct SyMRI model after multivariate Cox proportional hazards regression analysis