Fibrosis stage | n | Cut-off (kPa) | AUC (95% CI) | p | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Accuracy | |
---|---|---|---|---|---|---|---|---|---|---|
Liver stiffness (n = 52) | > F0 | 49 | 2.65 | 0.63 (0.49–0.85) | 0.302 | 40.8 (27–55.8) | 100 (29.2–100) | 100 (83.2–100) | 9.4 (2–25) | 44.2 |
> F1 | 35 | 2.14 | 0.76 (0.62–0.87) | < 0.001 | 91.4 (76.9–98.2) | 58.8 (32.9–81.6) | 82.1 (66.5–92.5) | 76.9 (46.2–95) | 80.8 | |
> F2 | 24 | 2.8 | 0.74 (0.56–0.85) | < 0.001 | 58.3 (36.6–77.9) | 85.7 (67.3–96) | 77.8 (52.4–93.6) | 70.6 (52.5–84.9) | 73.1 | |
> F3 | 11 | 2.97 | 0.90 (0.79–0.97) | < 0.001 | 90.9 (58.7–99.8) | 82.9 (67.9–92.8) | 58.8 (32.9–81.6) | 97.1 (85.1–99.9) | 84.6 | |
> F4 | 5 | 3.14 | 0.89 (0.78–0.96) | < 0.001 | 100 (47.8–100) | 80.9 (66.7–90.9) | 35.7 (12.8–64.9) | 100 (90.7–100) | 82.7 | |
> F5 | 4 | 3.14 | 0.86 (0.74–0.94) | < 0.001 | 100 (39.8–100) | 79.2 (65–89.5) | 28.6 (8.4–58.1) | 100 (90.7–100) | 80.8 | |
Spleen stiffness (n = 49) | > F0 | 46 | 0.5 | 0.64 (0.49–0.77) | 0.526 | 100 (92.3–100) | 33.3 (0.8–90.6) | 95.8 (85.7–99.5) | 100 (2.5–100) | 95.9 |
> F1 | 34 | 2.87 | 0.64 (0.49–0.77) | 0.112 | 73.5 (55.6–87.1) | 53.3 (26.6–78.7) | 78.1 (60–90.7) | 47.1 (23–72.2) | 67.3 | |
> F2 | 23 | 3.38 | 0.69 (0.55–0.82) | 0.010 | 73.9 (51.6–89.8) | 57.7 (36.9–76.6) | 60.7 (40.6–78.5) | 71.4 (47.8–88.7) | 65.3 | |
> F3 | 11 | 6.26 | 0.68 (0.54–0.81) | 0.083 | 45.5 (16.7–76.6) | 94.7 (82.3–99.4) | 71.4 (29–96.3) | 85.7 (71.5–94.6) | 83.7 | |
> F4 | 5 | 8.66 | 0.82 (0.69–0.92) | 0.002 | 60 (14.7–94.7) | 97.7 (88–99.9) | 75 (19.4–99.4) | 95.6 (84.9–99.5) | 93.9 | |
> F5 | 4 | 3.42 | 0.78 (0.64–0.89) | 0.030 | 100 (39.8–100) | 48.9 (33.7–64.2) | 14.8 (4.2–33.7) | 100 (84.6–100) | 53.1 |