Fig. 5

An application example of nomogram to predict the AR status. a A nomogram was constructed from four informative features. b Calibration curve for evaluating nomogram effectiveness fitted well. c Receiver operating characteristic curve of the model for predicting AR status. a and d In a 36-year-old (11 points) non-menopausal (37.5 points) woman with breast cancer, the B-mode ultrasound showed the tumor was 15 mm in diameter, the margin of the tumor was unsmooth (52.5 points), and the posterior acoustic pattern was shadowing (41 points) and BI-RADS 4c. The total points were about 142 and the probability of AR + predicted by our nomogram was about 82% in this case. e The immunohistochemistry result of the patient: nuclear staining was more than 10%, the expression of AR was positive, original magnification × 400. ROC, receiver operating characteristic; AUC, area under curve; AR, androgen receptor