Skip to main content

Table 2 Key imaging features observed on CT and MRI

From: CT and MR imaging features of mixed neuroendocrine–non-neuroendocrine neoplasm of the pancreas compared with pancreatic ductal adenocarcinoma and neuroendocrine tumor

 

MiNEN, n (%)

(n = 12)

PDAC, n (%)

(n = 24)

NET, n (%)

(n = 24)

p valuea

p valueb

κ value

Largest tumor diameter (cm)

 Mean ± SD

4.7 ± 2.3

3.0 ± 1.0

4.3 ± 2.3

0.031

0.589

0.98c

 Range

2.5–9.0

1.4–7.0

1.0–12.0

   

Tumor composition

   

0.003

0.722

0.74

 Purely solid

4 (33.3)

20 (83.3)

9 (37.5)

   

 Minor cystic

3 (25)

3 (12.5)

3 (12.5)

   

 Mixed solid and cystic

5 (41.7)

1 (4.2)

12 (50)

   

 Heterogeneity

10 (83.3)

8 (33.3)

21 (87.5)

0.012

> 0.999

0.89

Tumor margin

   

0.588

< 0.001

0.9

 Well-defined smooth

2 (16.7)

2 (8.3)

23 (95.8)

   

 Ill-defined irregular

10 (83.3)

22 (91.7)

1 (4.2)

   

Enhancement degree

   

< 0.001

< 0.001

0.88

 Mild

0 (0)

21 (87.5)

0 (0)

   

 Moderate

11 (91.7)

3 (12.5)

5 (20.8)

   

 Marked

1 (8.3)

0 (0)

19 (79.2)

   

Arterial enhancement pattern

   

0.247

0.479

0.77

 Rim type

5 (41.7)

5 (20.8)

7 (29.2)

   

 Diffuse type

7 (58.3)

19 (79.2)

17 (70.8)

   

Portal enhancement pattern

   

> 0.999

0.031

0.91

 Progressive enhancement

11 (91.7)

22 (91.7)

13 (54.2)

   

 Washout

1 (8.3)

2 (8.3)

11 (45.8)

   

 Tumor calcification

2 (16.7)

0 (0)

1 (4.2)

0.105

0.253

0.79

 Visible lymph nodes

2 (16.7)

7 (29.2)

2 (8.3)

0.685

0.588

0.88

 Bile duct dilatation

2 (16.7)

2 (8.3)

4 (16.7)

0.588

> 0.999

0.8

 Marked upstream MPD dilatation

5 (41.7)

10 (41.7)

12 (50)

> 0.999

0.732

0.9

 Adjacent organ involvement

6 (50)

13 (54.1)

3 (12.5)

> 0.999

0.036

0.82

 Vascular involvement

3 (25)

18 (75)

3 (12.5)

0.01

0.378

0.76

  1. Categorical variables are described as the number of patients with the percentage in parentheses
  2. CT, computed tomography; MRI, magnetic resonance imaging; MiNEN, mixed neuroendocrine–non-neuroendocrine neoplasm; PDAC, pancreatic ductal adenocarcinoma; NET, neuroendocrine tumor; MPD, main pancreatic duct
  3. aComparison between MiNEN and PDAC; b comparison between MiNEN and NET; c Intraclass correlation coefficients with 95% CIs were calculated for largest tumor diameter