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Insights into Imaging

Table 3 Clinical and CMR predictors of MACE in univariable cox regression analysis for patients with and without MVO

From: Prognostic significance of non-infarcted myocardium correlated with microvascular impairment evaluated dynamically by native T1 mapping

 

Univariable analysis

Unadj HR (95% CI)

p value

Clinical parameters

Killip class

2.47 (1.53, 4)

 < 0.001

cTnImax, ng/mL

1.01 (1.001, 1.02)

0.030

BNPmax, pg/mL

1.001 (1, 1.002)

0.030

CRPmax, mg/L

1.02 (1.01, 1.03)

0.004

TIMI flow grade pre-PCI

0.90 (0.65, 1.24)

0.505

TIMI flow grade post-PCI

0.37 (0.20, 0.70)

0.002

CMR imaging parameters

LVEDV1w, mL

1.01 (1, 1.02)

0.054

LVESV1w, mL

1.01 (1.002, 1.02)

0.017

iLVEDV1w, mL/m2

1.01 (0.99, 1.03)

0.211

iLVESV1w, mL/m2

1.02 (1, 1.03)

0.060

LVEF1w, %

0.93 (0.90, 0.97)

 < 0.001

LVEF30D, %

0.97 (0.93, 1.01)

0.142

LVEF6M, %

0.95 (0.92, 0.99)

0.013

LGE1w, %

1.10 (1.06, 1.14)

 < 0.001

LGE30D, %

1.12 (1.08, 1.17)

 < 0.001

LGE6M, %

1.05 (1.01, 1.09)

 < 0.001

Native1w T1

1.03 (1.02, 1.04)

 < 0.001

Native30D T1

1.04 (1.03, 1.05)

 < 0.001

Native6M T1

1.02 (1.01, 1.03)

0.004

Transmural infarction

5.26 (1.24, 22.27)

0.024

Pericardial effusion

3 (0.90, 10)

0.074

IMH

3.57 (1.07, 11.93)

0.038

MVO

2.95 (1.01, 8.56)

0.047

  1. Unadj HR, unadjusted hazard ratio; CI, confidence interval; cTnImax,peak troponin I; CK-MBmax, peak creatinine kinase-MB; BNPmax, peak brain natriuretic peptide; CRPmax, peak c-creative protein; TIMI flow grade post-PCI (1–2); TIMI flow was 1 or 2 after primary PCI; MVO, microvascular obstruction; IMH, intramyocardial hemorrhage; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; SV, stroke volume; LVEF, left ventricular ejection fraction; iLVEDV, indexed left ventricular end-diastolic volume; and LGE, late gadolinium enhancement
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