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Table 2 Left ventricular function and tissue characteristics of CMR in dynamic evolution

From: Prognostic significance of non-infarcted myocardium correlated with microvascular impairment evaluated dynamically by native T1 mapping

 

Total (n = 135)

MVO(−) (n = 49)

MVO(+) (n = 86)

p value

LVEDV, mL

    

 1 week

130. 56 (107.89, 151.79)

116.87 (99.54, 134)

141.17 (118.62, 159.38)

 < 0.001

 Day 30

132.60 (111, 161.50)

123 (102.47, 147)

143 (124, 179.16)

0.001

 6 Months

142.37 (113.90, 172)

127.43 (107.50, 158.76)

155.30 (117.17, 193.48)

0.020

LVESV, mL

    

 1 week

60 (49.10, 83.63)

51.32 (41.56, 65)

71.30 (52.56, 91.12)

 < 0.001

 Day 30

60 (43.23, 91.10)

44.47 (40.20, 72)

69.60 (51.76, 106.16)

 < 0.001

 6 Months

67 (49, 100.20)

58.3 (46.8, 78.6)

76 (58, 119)

0.001

SV, mL

    

 1 week

65.34 ± 16.94

63.63 ± 14.73

66.34 ± 18.10

0.340

 Day 30

69.05 ± 16.71

67.8 ± 15

70.1 ± 18.1

0.510

 6 Months

70.17 ± 16.64

72.56 ± 16.17

68.40 ± 16.90

0.220

LV mass, g/m2

    

 1 week

128.73 (106.57, 146)

112.55 (99.93, 133.95)

137.60 (117.30, 151.45)

 < 0.001

 Day 30

116.24 (100, 133.60)

114 (100, 126)

122 (104.11, 139.90)

0.080

 6 Months

111 (96.58, 132)

107 (95.50, 118.18)

121 (98.29, 142.35)

0.070

iLVEDV, mL/m2

    

 1 week

71.05 (62.09, 80.59)

66.09 (56.55, 77.23)

74.92 (65.93, 82.50)

0.001

 Day 30

74.33 (61.09, 90.65)

67.62 (55.75, 80.85)

77.82 (68.08, 96.41)

0.002

 6 Months

78.02 (65.11, 98.85)

71.06 (63.51, 87.82)

84.15 (67.06, 107.37)

0.030

iLVESV, mL/m2

    

 1 week

32.85 (27.57, 45.61)

29.50 (26.25, 34.12)

39.18 (28.66, 48.15)

 < 0.001

 Day 30

32.45 (24.93, 49.58)

26.97 (21.12, 37.82)

40.24 (28.66, 60.36)

 < 0.001

 6 Months

37.23 (27.34, 57.66)

31.55 (26.29, 44.13)

43.31 (29.73, 62.93)

0.001

iSV, mL/m2

    

 1 week

35.59 ± 7.87

36 ± 6.85

35.34 ± 8.43

0.610

 Day 30

37.97 ± 8.18

37.41 ± 7.47

38.44 ± 8.77

0.544

 6 Months

39.16 ± 8.79

40.63 ± 8.76

38.07 ± 8.73

0.150

iLV mass, g/m2

    

 1 week

68.74 (59.42, 80)

63.68 (56.44, 74.85)

72.70 (63.46, 82.88)

0.004

 Day 30

62.67 (57.51, 74)

60.28 (55.69, 72.10)

65.20 (58.23, 79.45)

0.140

 6 Months

62.38 (54.17, 74.36)

57.94 (54.47, 66.76)

67.43 (53.51, 75.57)

0.070

LVEF, %

    

 1 week

49 (42.84, 59)

56.50 (52, 62.97)

44.63 (40, 52.65)

0.001

 Day 30

54.25 (44, 60.08)

58.99 (54, 65)

47.07 (38.44, 55.47)

0.001

 6 Months

51.90 (40, 60)

59.73 (52.08, 69)

46.13 (37.45, 57.19)

0.003

LGE, %

    

 1 week

28.27 (16.30, 38.50)

18.70 (9.50, 27.47)

30.45 (27.25, 35.98)

 < 0.001

 Day 30

20 (12, 31.38)

11.30 (6.35, 17.92)

26.68 (18.13, 31.75)

 < 0.001

 6 Months

22 (12, 30.25)

11.50 (8.03, 24.10)

22.95 (14.80, 28.42)

0.002

Native T1 mapping

    

 1 week

1254 (1241, 1272)

1243 (1225, 1258.50)

1259.50(1248.25, 1276)

 < 0.001

 Day 30

1235 (1224.25, 12,426.75)

1225 (1211, 1239)

1239 (1230, 1250)

 < 0.001

 6 Months

1273 (1254, 1296)

1269.50 (1230, 1289.25)

1277 (1258.25, 1298.25)

0.087

Native T1Normal

1217 (1188.50, 1236.75)abc

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Transmural infarction

89 (65.90%)

17 (34.70%)

72 (83.70%)

 < 0.001

Pericardial effusion

90 (66.70%)

22 (44.90%)

68 (79.10%)

 < 0.001

IMH

89 (65.90%)

7 (14.30%)

82 (95.30%)

 < 0.001

  1. Numbers are given as median (inter-quartile ranges) or mean ± standard deviation or as absolute frequency with percentages in parentheses. p value represents comparison of patients with MVO and without MVO
  2. MVO, microvascular obstruction; IMH, intramyocardial hemorrhage. LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; SV, stroke volume; LVEF, left ventricular ejection fraction; iLVEDV, indexed left ventricular end-diastolic volume; and LGE, late gadolinium enhancement
  3. ap < 0.001, T11w and T1normal
  4. bp = 0.012, T130D and T1normal
  5. cp < 0.001, T16months and T1normal