Skip to main content
Insights into Imaging
Fig. 13 | Insights into Imaging

Fig. 13

From: Multimodality imaging of neurodegenerative disorders with a focus on multiparametric magnetic resonance and molecular imaging

Fig. 13

A 58-year-old man with notable agrammatism, impaired comprehension and repetition of syntactically complex sentences, and spared single word comprehension, Montreal Cognitive Assessment (MoCA) 16/30. T1-weighted volumetric image (a) demonstrates asymmetric atrophy of the left perisylvian and insular cortices (arrow). Fluorodeoxyglucose PET/MRI demonstrates hypometabolism in this region (arrow in b). Single-subject statistical parametric mapping of the FDG-PET/MRI (c) demonstrates the asymmetric left greater than right hypometabolism involving the frontal and temporal operculum and parietal lobes with sparing of the PCC and precuneus (as before, areas of blue progressing to purple represent further negative deviation from the mean uptake values of controls). Combining the clinical and imaging data, a diagnosis of nfPPA was rendered

Back to article page