Fig. 12

A 68-year-old man who presented to the memory care clinic with progressive personality changes and behavioral disturbances including violent outbursts and memory loss. Fluorodeoxyglucose PET/CT demonstrates marked frontal (a) and temporal (b) hypometabolism with relatively preserved parietal and occipital lobe activity including relative sparing of the PCC and precuneus. Single-subject statistical parametric mapping (c) from a similar patient demonstrates a similar pattern, with anterior greater than posterior cingulate hypometabolism, a hallmark of FTD, again with areas of blue progressing to purple representing further negative deviation from the mean uptake values of controls