A feasibility study of reduced full-of-view synthetic high-b-value diffusion-weighted imaging in uterine tumors

Insights into Imaging

Table 5 Diagnosis performance on cervical cancer of histogram-derived synthetic 13b-protocol and 5b-protocol ADC values with a b value of 0 and 1200 s/mm²

Parameters	AUC (95%CI)	Sensitivity (%)	Specificity (%)	p value	Threshold(s/mm²)
syADC_13b,mean	0.995 (0.985–1.000)	97.2	97.2	p < 0.05	0.941 × 10^–3
syADC_5b,mean	0.988 (0.967–1.000)	97.1	97.1	p < 0.05	0.934 × 10^–3
syADC_13b,minimum	0.961 (0.921–0.989)	94.4	88.9	p < 0.05	0.633 × 10^–3
syADC_5b,minimum	0.935 (0.869–1.000)	91.4	91.4	p < 0.05	0.654 × 10^–3
syADC_13b,skewness	0.485 (0.349–0.620)	55.6	55.6	p = 0.34	− 0.067
syADC_5b,skewness	0.452 (0.316–0.588)	8.6	74.3	p = 0.07	− 0.239
syADC_13b,kurtosis	0.485 (0.349–0.621)	11.1	97.2	p = 0.35	− 0.564
syADC_5b,kurtosis	0.387 (0.255–0.518)	28.6	48.6	p = 0.07	− 0.520

p values < 0.05 were considered statistically significant and are shown in bolded font
AUC = area under the receiver operating characteristic curve, 95%CI = 95% confidence intervals, syADC = synthetic apparent diffusion coefficient