A feasibility study of reduced full-of-view synthetic high-b-value diffusion-weighted imaging in uterine tumors

Insights into Imaging

Table 3 Diagnosis performance on cervical cancer of histogram-derived scanned and synthetic 13b-protocol ADC values with a b value of 0 and 1200 s/mm²

Parameters	AUC (95%CI)	Sensitivity (%)	Specificity (%)	p value	Threshold (s/mm²)
sADC_13b,mean	0.995 (0.987–1.000)	100.0	94.4	p < 0.05	0.903 × 10^–3
syADC_13b,mean	0.995 (0.985–1.000)	97.2	97.2	p < 0.05	0.941 × 10^–3
sADC_13b,minimum	0.956 (0.716–0.909)	91.7	88.9	p < 0.05	0.573 × 10^–3
syADC_13b,minimum	0.961 (0.921–1.000)	94.4	88.9	p < 0.05	0.633 × 10^–3
sADC_13b,skewness	0.463 (0.328–0.598)	91.7	16.7	p = 0.33	− 0.515
syADC_13b,skewness	0.485 (0.349–0.620)	55.6	55.6	p = 0.34	− 0.067
sADC_13b,kurtosis	0.439 (0.300–0.579)	97.2	22.2	p = 0.30	− 0.793
syADC_13b,kurtosis	0.485 (0.349–0.621)	11.1	97.2	p = 0.35	− 0.564

p values < 0.05 were considered statistically significant and are shown in bolded font
AUC = area under the receiver operating characteristic curve, 95%CI = 95% confidence intervals, sADC = scanned apparent diffusion coefficient, syADC = synthetic apparent diffusion coefficient