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Table 3 Clinical predictive factors according to univariate and multivariate logistic regression in the training set

From: Added value of histogram analysis of ADC in predicting radiation-induced temporal lobe injury of patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy

 

Univariate analysis

Multivariate analysis

Coefficient

OR (95% CI)

p

Coefficient

OR (95% CI)

p

Age

0.01

1.01 (0.986–1.039)

0.37

   

Sex

− 0.15

0.86 (0.152–1.575)

0.69

   

NLRs

0.13

1.14 (0.932–1.356)

0.21

   

T stage

1.12

3.07 (2.516–3.618)

 < 0.001

0.88

2.41 (1.204–5.724)

0.02*

N stage

− 0.18

0.83 (0.450–1.218)

0.35

   

TNM stage

0.96

2.60 (1.996–3.211)

0.002

0.18

1.19 (0.450–2.883)

0.70

Pathology

− 0.02

0.98 (0.256–1.714)

0.97

   

Treatment

− 0.18

0.83 (0.577–1.085)

0.15

   

PGTVNX

0.35

1.42 (1.105–1.735)

0.03

0.19

1.21 (0.878–1.771)

0.26

LDmax

0.07

1.07 (1.006–1.131)

0.04

− 0.02

0.98 (0.898–1.073)

0.70

RDmax

0.10

1.11 (1.037–1.176)

0.004

0.08

1.08 (0.984–1.194)

0.11

  1. CI = confidence interval, LDmax = maximum dose of left temporal lobe, NLRs = neutrophil-to-lymphocyte ratios, OR = odds ratio, PGTVNX = planning gross tumor volume included the primary nasopharyngeal tumor or enlarged retropharyngeal nodes, RDmax = maximum dose of right temporal lobe, TNM = tumor-node-metastasis. * indicates significant difference