From: Radiomics assessment of carotid intraplaque hemorrhage: detecting the vulnerable patients
Clinical factors | Training set (n = 106) | External test set (n = 38) | ||||
---|---|---|---|---|---|---|
Plaques with IPH (n = 46) | Plaques without IPH (n = 60) | p | Plaques with IPH (n = 18) | Plaques without IPH (n = 20) | p | |
Age, y | 65.4 ± 9.4 | 62.0 ± 8.1 | 0.55 | 63.7 ± 9.4 | 65.0 ± 8.0 | 0.653 |
Sex, male | 39 (84.8%) | 47 (78.3%) | 0.460 | 12 (66.7%) | 18 (90.0%) | 0.117 |
BMI, kg/m2 | 25.9 ± 1.4 | 26.5 ± 1.8 | 0.89 | 26.6 ± 1.4 | 26.4 ± 1.3 | 0.747 |
Hypertension | 34 (73.9%) | 50 (83.3%) | 0.334 | 16 (88.9%) | 7 (35.0%) | 0.001 |
Hyperlipidemia | 23 (50.0%) | 27 (45.0%) | 0.696 | 13 (72.2%) | 8 (40.0%) | 0.058 |
Diabetes | 17 (37.0%) | 17 (28.3%) | 0.404 | 3 (16.7%) | 0 (0%) | 0.097 |
Smoking | 25 (54.3%) | 31 (51.7%) | 0.846 | 11 (61.1%) | 17 (85.0%) | 0.144 |
CAD | 24 (52.2%) | 21 (35.0%) | 0.112 | 11 (61.1%) | 7 (35.0%) | 0.193 |
Antihypertension use | 29 (63.0%) | 33 (55.0%) | 0.433 | 15 (83.3%) | 4 (20.0%) | < 0.001 |
Statin use | 25 (54.3%) | 31 (51.7%) | 0.846 | 8 (44.4%) | 7 (35.0%) | 0.741 |
Antiplatelet use | 21 (45.7%) | 31 (51.7%) | 0.562 | 9 (50.0%) | 11 (55.0%) | 0.758 |
Calcification | 36 (78.3%) | 51 (85.0%) | 0.447 | 12 (66.7%) | 15 (75.0%) | 0.724 |
Degree of stenosis, % | 48.5 ± 19.5 | 32.6 ± 15.8 | < 0.001 | 40.3 ± 21.8 | 36.4 ± 16.5 | 0.540 |
Maximum thickness, mm | 4.0 ± 1.6 | 2.9 ± 1.0 | < 0.001 | 4.2 ± 1.3 | 2.7 ± 0.9 | < 0.001 |
Ulceration | 6 (13.0%) | 0 (0%) | 0.005 | 3 (16.7%) | 0 (0%) | 0.097 |