Table 3 Clinical and body composition characteristics of patients after propensity scoring-matched (PSM) analysis
Variables | Total (n = 90) | EAD (n = 45) | No EAD (n = 45) | p value |
|---|---|---|---|---|
Age (years), median (IQR) | 50 (42–54) | 50 (41–55) | 48 (42–53) | 0.324 |
Gender (M/F), N (%) | 81/9 (90.0/10.0) | 39/6 (86.7/13.3) | 42/3 (93.3/6.7) | 0.482 |
BMI (kg/m2), median (IQR) | 22.9 (20.7–24.8) | 22.9 (20.8–24.7) | 22.7 (20.7–25.5) | 0.993 |
Viral status, N (%) | 0.221 | |||
HBV/HCV/HBV + HCV/none | 72/3/1/14 (80.0/3.3/1.1/15.6) | 33/1/1/10 (73.3/2.2/2.2/22.2) | 39/2/0/4 (86.7/4.4/0.0/8.9) | |
Etiology, N (%) | 0.780 | |||
Viral hepatitis | 33 (36.7%) | 16 (35.6%) | 17 (37.8%) | |
Alcoholic cirrhosis | 4 (4.4%) | 2 (4.4%) | 2 (4.4%) | |
Hepatocellular carcinoma | 49 (54.4%) | 24 (53.3%) | 25 (55.6%) | |
Primary biliary cirrhosis & Autoimmune liver disease | 3 (3.3%) | 2 (4.4%) | 1 (2.2%) | |
Other | 1 (1.1%) | 1 (2.2%) | 0 (0.0%) | |
Coexisting conditions, N (%) | ||||
Smoking | 39 (43.3%) | 17 (37.8%) | 22 (48.9%) | 0.288 |
Drinking | 27 (30.0%) | 12 (26.7%) | 15 (33.3%) | 0.490 |
Hypertension | 5 (11.1%) | 4 (8.9%) | 1 (2.2%) | 0.357 |
Diabetes | 8 (8.9%) | 4 (8.9%) | 4 (8.9%) | > 0.999 |
Cardiovascular and cerebrovascular disease | 3 (3.3%) | 2 (4.4%) | 1 (2.2%) | > 0.999 |
Chronic kidney disease | 2 (2.2%) | 1 (2.2%) | 1 (2.2%) | > 0.999 |
Hepatic features | ||||
Child–Pugh class A/B/C, N (%) | 45/36/9 (50.0/40.0/10.0) | 24/14/7 (53.3/31.1/15.6) | 21/22/2 (46.7/48.9/4.4) | 0.085 |
Child–Pugh score, median (IQR) | 7 (5–8) | 6 (5–9) | 7 (5–8) | 0.798 |
MELD Score, median (IQR) | 12 (9–16) | 12 (9–17) | 13 (8–16) | 0.987 |
Preoperative laboratory values | ||||
ALT (U/L), median (IQR) | 29 (19–51) | 27 (19–53) | 30 (19–49) | 0.824 |
AST (U/L), median (IQR) | 40 (28–71) | 40 (27–73) | 39 (29–62) | 0.929 |
ALP (U/L), median (IQR) | 105 (82–140) | 104 (84–141) | 105 (78–139) | 0.837 |
LDH (U/L), median (IQR) | 201 (174–270) | 204 (177–270) | 198 (173–269) | 0.865 |
Total bilirubin (μmol/L), median (IQR) | 31.0 (16.6–74.8) | 29.7 (17.9–82.2) | 36.5 (12.4–76.5) | 0.862 |
Albumin (g/L), median (IQR) | 35.8 (31.4–40.2) | 35.8 (31.7–40.7) | 35.8 (31.1–40.2) | 0.842 |
Creatinine (μmol/L), median (IQR) | 68 (59–75) | 69 (60–73) | 66 (58–79) | 0.762 |
Blood Ammonia(μmol/L), median (IQR) | 56 (46–73) | 57 (48–63) | 56 (41–75) | 0.900 |
Neutrophil (× 109/L), median (IQR) | 2.44 (1.52–4.27) | 2.51 (1.31–4.57) | 2.39 (1.67–4.09) | 0.594 |
Lymphocyte (× 109/L), median (IQR) | 1.09 (0.63–1.49) | 1.10 (0.64–1.55) | 1.09 (0.61–1.47) | 0.815 |
Platelet (× 109/L), median (IQR) | 76 (50–162) | 84 (51–132) | 68 (49–174) | 0.981 |
NLR, median (IQR) | 2.60 (1.71–4.82) | 2.33 (1.60–4.77) | 2.75 (1.83–4.92) | 0.490 |
PLR, median (IQR) | 82.61 (60.68–143.02) | 78.26 (60.87–139.49) | 90.00 (56.44–145.11) | 0.821 |
Prothrombin time(s), median (IQR) | 16.5 (14.5–19.1) | 16.4 (14.2–20.2) | 16.6 (14.6–18.7) | 0.834 |
INR, median (IQR) | 1.33 (1.13–1.62) | 1.32 (1.12–1.73) | 1.35 (1.14–1.54) | 0.929 |
Body composition variable | ||||
SMA (cm2), median (IQR) | 143.4 (127.6–162.2) | 143.4 (123.5–158.8) | 142.0 (127.7–164.4) | 0.588 |
SMD (HU), median (IQR) | 45.5 (39.6–50.1) | 44.4 (36.6–49.7) | 45.8 (41.4–50.7) | 0.059 |
SAT (cm2), median (IQR) | 98.9 (69.3–130.1) | 107.4 (73.6–135.3) | 90.6 (57.7–131.8) | 0.503 |
VAT (cm2), median (IQR) | 84.6 (51.8–127.4) | 88.2 (59.1–141.8) | 73.0 (30.1–122.7) | 0.047 |
VSR, median (IQR) | 0.86 (0.60–1.08) | 0.93 (0.70–1.21) | 0.80 (0.57–0.99) | 0.042 |
IMAT (cm2), median (IQR) | 3.0 (2.0–4.7) | 3.3 (2.4–5.8) | 2.5 (1.8–4.2) | 0.042 |