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Table 1 Clinical and body composition characteristics of the patients

From: High visceral adipose tissue area is independently associated with early allograft dysfunction in liver transplantation recipients: a propensity score analysis

Variables

Total

(n = 175)

EAD

(n = 55)

No EAD

(n = 120)

p value

Age (years), median (IQR)

49 (42–54)

43 (50–55)

49 (41–54)

0.435

Gender (M/F), N (%)

142/33 (81.1/18.9)

49/6 (89.1/10.9)

93/27 (77.5/22.5)

0.069

BMI (kg/m2), median (IQR)

22.5 (20.3–24.7)

23.2 (20.8–24.9)

22.0 (19.9–24.2)

0.019

Viral status, N (%)

   

0.316

HBV/HCV/HBV + HCV/None

132/8/1/34 (75.4/4.6/0.6/19.4)

42/1/1/11(76.4/1.8/1.8/20.0)

90/7/0/23 (75.0/5.8/0.0/19.2)

 

Etiology, N (%)

   

0.377

 Viral hepatitis

67 (38.3%)

20 (36.4%)

47 (39.2%)

 

 Alcoholic cirrhosis

6 (3.4%)

2 (3.6%)

4 (3.3%)

 

 Hepatocellular carcinoma

80 (45.7%)

29 (52.7%)

51 (42.5%)

 

 Primary biliary cirrhosis and Autoimmune liver disease

14 (8.0%)

2 (3.6%)

12 (10.0%)

 

 Other

8 (4.6%)

2 (3.6%)

6 (10.9%)

 

Coexisting conditions, N (%)

    

 Smoking

70 (40.0%)

22 (40.0%)

48 (40.0%)

> 0.999

 Drinking

54 (30.9%)

18 (32.7%)

36 (30.0%)

0.717

 Hypertension

15 (8.6%)

6 (10.9%)

9 (7.5%)

0.455

 Diabetes

18 (10.3%)

4 (7.3%)

14 (11.7%)

0.434

 Cardiovascular and cerebrovascular disease

8 (4.6%)

3 (5.5%)

5 (4.2%)

0.709

 Chronic kidney disease

2 (1.1%)

1 (1.8%)

1 (0.8%)

0.531

Hepatic features

    

 Child–Pugh class A/B/C, N (%)

88/70/17 (50.3/40.0/9.7)

26/20/9 (47.3/36.4/16.4)

62/50/8 (51.7/41.7/6.7)

0.131

 Child–Pugh score, median (IQR)

6 (5–8)

7 (5–9)

6 (5–8)

0.189

 MELD Score, median (IQR)

12 (9–18)

13 (9–18)

12 (8–17)

0.507

Preoperative laboratory values

    

 ALT (U/L), median (IQR)

29 (19–47)

31 (20–54)

29 (18–45)

0.423

 AST (U/L), median (IQR)

39 (28–72)

44 (27–77)

39 (28–64)

0.522

 ALP (U/L), median (IQR)

104 (79–155)

106 (83–144)

103 (76–163)

0.778

 LDH (U/L), median (IQR)

209 (171–267)

207 (173–271)

209 (166–261)

0.714

 Total bilirubin (μmol/L), median (IQR)

30.6 (16.7–79.2)

31.6 (18.4–99.7)

27.4 (14.9–73.1)

0.411

 Albumin (g/L), median (IQR)

36.2 (31.9–40.8)

35.4 (31.4–39.2)

37.1 (32.6–41.4)

0.085

 Creatinine (μmol/L), median (IQR)

68 (57–76)

69 (61–75)

66 (56–76)

0.584

 Blood ammonia(μmol/L), median (IQR)

57 (44–74)

60 (49–79)

55 (43–74)

0.299

 Neutrophil (× 109/L), median (IQR)

2.58 (1.53–4.57)

2.61 (1.35–5.37)

2.47 (1.59–3.94)

0.908

 Lymphocyte (× 109/L), median (IQR)

0.95 (0.56–1.39)

1.00 (0.51–1.42)

0.89 (0.57–1.36)

0.742

 Platelet (× 109/L), median (IQR)

72 (44–131)

84 (51–139)

63 (42–128)

0.113

 NLR, median (IQR)

2.71 (1.90–4.98)

2.50 (1.64–5.80)

2.80 (1.92–4.86)

0.726

 PLR, median (IQR)

86.67 (56.53–138.52)

104.43 (65.77–170.0)

84.61 (51.68–132.48)

0.100

 Prothrombin time(s), median (IQR)

16.6 (14.6–19.6)

16.6 (14.5–20.1)

16.6 (14.6–19.5)

0.890

 INR, median (IQR)

1.35 (1.14–1.65)

1.36 (1.13–1.72)

1.35 (1.14–1.64)

0.900

Body composition variable

    

 SMA (cm2), median (IQR)

137.3 (113.2–156.4)

143.4 (123.0–166.2)

132.2 (109.4–156.2)

0.075

 SMD (HU), median (IQR)

37.3 (43.6–47.9)

43.0 (34.2–48.6)

44.0 (38.7–47.7)

0.350

 SAT (cm2), median (IQR)

90.6 (61.5–131.5)

109.3 (76.0–149.2)

84.6 (49.5–128.4)

0.013

 VAT (cm2), median (IQR)

77.9 (49.3–120.7)

101.0 (61.3–157.0)

69.6 (39.1–108.0)

< 0.001

 VSR, median (IQR)

0.87 (0.64–1.14)

0.95 (0.71–1.22)

0.86 (0.60–1.08)

0.084

 IMAT (cm2), median (IQR)

3.1 (2.0–5.4)

3.4 (2.4–6.0)

2.9 (1.9–5.2)

0.068

  1. The bold indicated the items with statistically significant difference between the two groups
  2. EAD, early allograft dysfunction; BMI, body mass index; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, model for end‐stage liver disease; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; NLR, Neutrophil–lymphocyte ratio; PLR, platelet–lymphocyte ratio; INR, international normalized ratio; SMA, skeletal muscle area; SMD, the mean attenuation of skeletal muscle; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; VSR, visceral to subcutaneous adipose tissue area ratio; IMAT, intramuscular adipose tissue