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Insights into Imaging

Table 1 Mean IVIM parameters at different time points during the course of CI-AKI

From: Evaluation of contrast-induced acute kidney injury using IVIM and DKI MRI in a rat model of diabetic nephropathy

 

Group

Baseline

1 h

24 h

48 h

72 h

D (× 10–3 mm2/s)

      

 CO

LOCM

1.54 ± 0.10

1.42 ± 0.01*

1.37 ± 0.01*

1.34 ± 0.01*

1.33 ± 0.01*

 

IOCM

 

1.42 ± 0.01*

1.38 ± 0.01*

1.36 ± 0.02*

1.39 ± 0.01*

 OM

LOCM

1.55 ± 0.04

1.47 ± 0.04*

1.41 ± 0.01*

1.38 ± 0.15*

1.37 ± 0.01*

 

IOCM

 

1.49 ± 0.01*

1.42 ± 0.01*

1.41 ± 0.08*

1.38 ± 0.01*

 IM

LOCM

1.58 ± 0.07

1.48 ± 0.01*

1.38 ± 0.23

1.38 ± 0.01*

1.37 ± 0.01*

 

IOCM

 

1.49 ± 0.01*

1.43 ± 0.01

1.41 ± 0.01*

1.39 ± 0.02*

D* (× 10–3 mm2/s)

      

 CO

LOCM

18.55 ± 0.68

12.77 ± 0.16*

10.64 ± 0.02*

9.80 ± 0.05*

10.31 ± 0.26*

 

IOCM

 

13.55 ± 0.29*

11.56 ± 0.28*

12.50 ± 0.25*

12.71 ± 0.20*

 OM

LOCM

20.02 ± 0.26

14.83 ± 1.21*

13.15 ± 0.02*

12.33 ± 0.21*

13.50 ± 0.29*

 

IOCM

 

15.65 ± 0.12*

13.87 ± 0.04*

14.50 ± 0.24*

15.05 ± 0.46*

 IM

LOCM

19.19 ± 0.31

13.08 ± 0.62*

12.23 ± 1.00*

11.53 ± 0.24*

12.26 ± 0.14*

 

IOCM

 

14.34 ± 0.04*

13.13 ± 0.18*

13.46 ± 0.18*

14.28 ± 0.28*

f (%)

      

 CO

LOCM

16.80 ± 1.10

14.70 ± 1.22*

12.76 ± 1.64*

11.71 ± 0.60*

12.68 ± 1.27*

 

IOCM

 

14.90 ± 1.46

13.76 ± 1.15*

12.62 ± 0.63*

13.10 ± 0.26*

 OM

LOCM

17.16 ± 1.08

15.31 ± 0.83

14.22 ± 1.88*

13.20 ± 1.49*

13.18 ± 1.08*

 

IOCM

 

15.21 ± 2.12*

14.79 ± 1.10*

14.65 ± 1.74*

15.23 ± 0.27*

 IM

LOCM

17.12 ± 1.16

15.27 ± 0.95

14.77 ± 2.75

12.33 ± 1.05*

11.69 ± 1.86*

 

IOCM

 

14.31 ± 1.84*

15.25 ± 1.12

13.82 ± 0.91*

14.58 ± 3.05

MD (× 10–3 mm2/s)

      

 CO

LOCM

3.20 ± 0.16

3.18 ± 0.03

3.10 ± 0.03

2.86 ± 0.13*

2.76 ± 0.20*

 

IOCM

 

3.19 ± 0.06

2.91 ± 0.006

2.80 ± 0.03*

2.77 ± 0.09*

 OM

LOCM

2.29 ± 0.24

2.37 ± 0.02

2.25 ± 0.03

2.06 ± 0.05

1.77 ± 0.10*

 

IOCM

 

2.36 ± 0.17

2.33 ± 0.17

2.26 ± 0.15

1.88 ± 0.07*

 IM

LOCM

2.36 ± 0.26

2.39 ± 0.22

2.33 ± 0.24

2.24 ± 0.37

2.24 ± 0.29

 

IOCM

 

2.31 ± 0.24

2.31 ± 0.14

2.11 ± 0.19

2.08 ± 0.24

MK

      

 CO

LOCM

0.76 ± 0.03

0.74 ± 0.01

0.76 ± 0.04

0.78 ± 0.05

0.85 ± 0.12

 

IOCM

 

0.75 ± 0.06

0.75 ± 0.03

0.76 ± 0.10

0.77 ± 0.09

 OM

LOCM

0.81 ± 0.01

0.77 ± 0.02*

0.84 ± 0.04

0.86 ± 0.02

0.90 ± 0.04*

 

IOCM

 

0.78 ± 0.03*

0.82 ± 0.06

0.85 ± 0.08

0.86 ± 0.04

 IM

LOCM

0.80 ± 0.14

0.71 ± 0.02

0.72 ± 0.03

0.76 ± 0.10

0.82 ± 0.08

 

IOCM

 

0.71 ± 0.02

0.71 ± 0.04

0.74 ± 0.07

0.78 ± 0.10

  1. *Represents p < 0.05 versus baseline
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