Arterial spin labeling of nasopharyngeal carcinoma shows early therapy response

Insights into Imaging

Table 5 Diagnostic efficacy of ASL-derived parameters in predicting PR and SD and residual and non-residual tumors

Parameters	Cutoff value (mL·100 g⁻¹·min⁻¹)	AUC (95% CI)	Sensitivity	Specificity
Pre-TBF^a	137.07	0.845 (0.739,0.951)	0.861	0.684
Post-TBF^a	87.03¹	0.686 (0.541,0.830)	0.583	0.789
ΔTBF^a	57.52	0.773 (0.638,0.909)	0.806	0.684
Pre-TBF^b	140.87	0.831 (0.706,0.957)	0.816	0.824
Post-TBF^b	82.71	0.676 (0.511,0.842)	0.658	0.706
ΔTBF^b	50.94	0.782 (0.642,0.922)	0.895	0.588

PR the partial response group; SD the stable disease group; Pre-TBF pre-treatment tumor blood flow; Post-TBF post-treatment tumor blood flow; ΔTBF changes in tumor blood flow; AUC area under the curve; CI confidence interval
^athe PR group and the SD group
^bthe residual and non-residual tumors