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Table 3 ICG-R15 and tomoelastography indexes between patients with different liver fibrosis grades

From: Tomoelastography based on multifrequency MR elastography predicts liver function reserve in patients with hepatocellular carcinoma: a prospective study

Liver fibrosis frade

F1–2 (n = 21)

F3–4 (n = 48)

p value

ICG-R15, % (range)

4.9 (1.8–14.0)

9.2 (1.3–48.0)

*0.005

Liver

 c (m/s)

1.64 ± 0.14

2.13 ± 0.42

* < 0.001

 φ (rad)

0.70 ± 0.07

0.82 ± 0.12

* < 0.001

Age, years (range)

58 ± 12 (38–81)

58 ± 9 (38–74)

0.937

Sex (male/female)

18:2

31:10

0.325

BMI (kg/m2)

24.1 ± 3.3

23.5 ± 2.9

0.501

Laboratory results

 ALB (g/L)

39.29 ± 4.57

38.73 ± 6.98

0.739

 PAB (mg/L)

208.05 ± 60.8

170.00 ± 61.85

*0.021

 TB (μmol/L)

16.39 ± 4.50

22.13 ± 13.56

0.066

 AST (U/L)

26.0 (23.5, 42.5)

35.5 (24.5, 56.8)

0.196

 ALT (U/L)

30.0 (19.5, 60.0)

25.5 (20.0, 41.3)

0.393

 PLT (×109/L)

172.25 ± 53.32

111.39 ± 49.03

* < 0.001

 PT (s)

12.24 ± 1.09

12.94 ± 1.36

*0.042

 INR

1.04 ± 0.09

1.10 ± 0.12

*0.039

  1. ICG-R15: 15-min indocyanine green retention rate, BMI: body mass index, ALB: albumin, PAB: prealbumin, TB: total bilirubin, AST: aspartate aminotransferase, ALT: alanine aminotransferase, PLT: platelet, PT: prothrombin time, INR: international normalized ratio
  2. *p < 0.05